2003 Vol. 30 No. 04
2003, 30(04): 253-255.
DOI: 10.3971/j.issn.1000-8578.2269
Abstract：
Objective To investigate the extent of basic fibroblast growth factor (bFGF) and fibroblast growth factor receptor 1 (FGFR 1) expression in human meningiomas and the relationship between the expression and the tumors' histological features and recurrence. Methods Expression of bFGF and FGFR 1 were examined by immunohistochemical technique. Results There is varied degree expression of bFGF and FGFR 1 protein in meningiomas. The expression correlates with the tumors' histological characters and recur...
Objective To investigate the extent of basic fibroblast growth factor (bFGF) and fibroblast growth factor receptor 1 (FGFR 1) expression in human meningiomas and the relationship between the expression and the tumors' histological features and recurrence. Methods Expression of bFGF and FGFR 1 were examined by immunohistochemical technique. Results There is varied degree expression of bFGF and FGFR 1 protein in meningiomas. The expression correlates with the tumors' histological characters and recur...
2003, 30(04): 256-258.
DOI: 10.3971/j.issn.1000-8578.2710
Abstract：
Objective To study the expression of CD44v5+ cells in different tissue of patients with gastric carcinoma. Methods The percentage of CD44v5+ cells was measured and analyzed in cancer nests, para cancer tissue, cancer metastasis lymph nodes and peripheral blood cells of patients with gastric carcinoma by flow cytometry. Results The percentage of CD44v5+ cells in tissues and peripheral blood of gastric carcinoma were significantly higher than those of normal control ( P < 0.05 and P < 0.01 )...
Objective To study the expression of CD44v5+ cells in different tissue of patients with gastric carcinoma. Methods The percentage of CD44v5+ cells was measured and analyzed in cancer nests, para cancer tissue, cancer metastasis lymph nodes and peripheral blood cells of patients with gastric carcinoma by flow cytometry. Results The percentage of CD44v5+ cells in tissues and peripheral blood of gastric carcinoma were significantly higher than those of normal control ( P < 0.05 and P < 0.01 )...
2003, 30(04): 259-261.
DOI: 10.3971/j.issn.1000-8578.2272
Abstract：
Objective To study the expression and significance of bcl-2 and p16 in esophageal squamous cell cancer and the surrounding tissues. Methods S-P method was used to examine the expression of bcl-2 and p16 in 40 esophageal squamous cell cancer and the surrounding tissues. Results Expression of bcl-2 was 6%, 63.3%, 46.5% and 42.5% in normal esophageal mucosa, atypical hyperplasia, and squamous carcinoma tissues, respedively. There were significant differences between normal esophageal mucosa and ot...
Objective To study the expression and significance of bcl-2 and p16 in esophageal squamous cell cancer and the surrounding tissues. Methods S-P method was used to examine the expression of bcl-2 and p16 in 40 esophageal squamous cell cancer and the surrounding tissues. Results Expression of bcl-2 was 6%, 63.3%, 46.5% and 42.5% in normal esophageal mucosa, atypical hyperplasia, and squamous carcinoma tissues, respedively. There were significant differences between normal esophageal mucosa and ot...
2003, 30(04): 262-264.
DOI: 10.3971/j.issn.1000-8578.2270
Abstract：
Objective This study was to investigate the expression of different nitric oxide synthase isozymes(NOSII-III) and vascular endothelial growth factor in the primary esophageal squamous cell carcinomas. A further analysis was performed to correlate the immunohistochemical data with tumor angiogenesis and clinicopathologic features. Methods Surgical specimens from 75 primary esophageal squamous cell carcinomas were examined for iNOS,cNOS,VEGF expression and micro vessel density by immunocytochemical staini...
Objective This study was to investigate the expression of different nitric oxide synthase isozymes(NOSII-III) and vascular endothelial growth factor in the primary esophageal squamous cell carcinomas. A further analysis was performed to correlate the immunohistochemical data with tumor angiogenesis and clinicopathologic features. Methods Surgical specimens from 75 primary esophageal squamous cell carcinomas were examined for iNOS,cNOS,VEGF expression and micro vessel density by immunocytochemical staini...
2003, 30(04): 265-267.
DOI: 10.3971/j.issn.1000-8578.2267
Abstract：
Objective To investigate the role of p27 kip1, cyclinE protein and PCNA on the occurrence and progress of pancreatic cancer. Methods Expression of p27 kip1, cyclinE and PCNA in tumor tissues and adjacent tissues of 32 patients with pancreatic cancer was studied by SP immunohistochemical technique. Results p27 kip1 protein positive-expression rate in tumor tissues of pancreatic cancer was 56.3%, which was lower than that in adjacent tissues (P< 0.05), p27 kip1 protein positive-expression co...
Objective To investigate the role of p27 kip1, cyclinE protein and PCNA on the occurrence and progress of pancreatic cancer. Methods Expression of p27 kip1, cyclinE and PCNA in tumor tissues and adjacent tissues of 32 patients with pancreatic cancer was studied by SP immunohistochemical technique. Results p27 kip1 protein positive-expression rate in tumor tissues of pancreatic cancer was 56.3%, which was lower than that in adjacent tissues (P< 0.05), p27 kip1 protein positive-expression co...
2003, 30(04): 268-269.
DOI: 10.3971/j.issn.1000-8578.2265
Abstract：
Objective To study the expression levels of hTERTand its clincopathological significances in 98 cases with chronic pancreatitis,and para-cancerous tissues, and pancreatic cancinoma respectively. Methods Immunohistochemical method of ABC was used. Results The positive rate and score of hTERT were significantly lower in chronic pancreatitis than those in para-cancerous tissues or pancreatic carcinoma, also they were significantly lower in pericancerous tissues than those in pancreatic carcinoma.The benig...
Objective To study the expression levels of hTERTand its clincopathological significances in 98 cases with chronic pancreatitis,and para-cancerous tissues, and pancreatic cancinoma respectively. Methods Immunohistochemical method of ABC was used. Results The positive rate and score of hTERT were significantly lower in chronic pancreatitis than those in para-cancerous tissues or pancreatic carcinoma, also they were significantly lower in pericancerous tissues than those in pancreatic carcinoma.The benig...
2003, 30(04): 270-272.
DOI: 10.3971/j.issn.1000-8578.2263
Abstract：
Objective To probe the role of ras oncogene p21 product and IGF-II in the development of cirrhotic nodules and hepatocellular carcinoma(HCC). Methods S-P immunohistochemical technique was used to analyze the expression of p21 and IGF-II was studied in 50 cases of liver cirrhosis without HCC, 28 cases of precancerous liver cirrhotic tissues, and 22 HCC cases. Results The positive rates for p21 and IGF-II in cirrhosis with or without HCC were significantly higher than these for HCC (P< 0.05). The posit...
Objective To probe the role of ras oncogene p21 product and IGF-II in the development of cirrhotic nodules and hepatocellular carcinoma(HCC). Methods S-P immunohistochemical technique was used to analyze the expression of p21 and IGF-II was studied in 50 cases of liver cirrhosis without HCC, 28 cases of precancerous liver cirrhotic tissues, and 22 HCC cases. Results The positive rates for p21 and IGF-II in cirrhosis with or without HCC were significantly higher than these for HCC (P< 0.05). The posit...
2003, 30(04): 273-275.
DOI: 10.3971/j.issn.1000-8578.2260
Abstract：
Objective To study the proapoptotic effect of Sodium Salicylate (Na-Sal) on the HL-60 Cells and its relation ship to the changes of intracellular free Ca 2+. Methods The phosphatidylserine exposure was measured by Annexin-V binding assay; DNA fragmentation detected by agarose gel electrophoresis; and the changes of the concentration of intracellular free Ca 2+ analyzed by confocal laser scanning microscope (CLSM). Results After treated with 5mmol/L(IC 50) Na-Sal for 10hs and 16hs, respectively,...
Objective To study the proapoptotic effect of Sodium Salicylate (Na-Sal) on the HL-60 Cells and its relation ship to the changes of intracellular free Ca 2+. Methods The phosphatidylserine exposure was measured by Annexin-V binding assay; DNA fragmentation detected by agarose gel electrophoresis; and the changes of the concentration of intracellular free Ca 2+ analyzed by confocal laser scanning microscope (CLSM). Results After treated with 5mmol/L(IC 50) Na-Sal for 10hs and 16hs, respectively,...
2003, 30(04): 276-277.
DOI: 10.3971/j.issn.1000-8578.2261
Abstract：
Objective To explore the influence of the level of IL-2 in pleural fluid on the increasing rate and anti-tumor effect of tumor-infiltrating lymphocytes (TIL) derived from malignant pleural fluid in vitro. Methods The levels of IL-2 in pleural fluid were measured by ELISA. MTT assay was used to detect the cytotoxicities against Lovo cell line of the TILs. Results The increase rate of TIL at the group with lower level of IL-2 was rapid than that of group with higher IL-2 level. The cytotoxicities against Lovo cell lines at the group with lower level of IL-2 were stronger than that of group with higher IL-2 level. Conclusion The level of IL-2 in pleural fluid relates to the increasing rate and cytotoxicity against tumor cells of the TILs. ReplaceFont
Objective To explore the influence of the level of IL-2 in pleural fluid on the increasing rate and anti-tumor effect of tumor-infiltrating lymphocytes (TIL) derived from malignant pleural fluid in vitro. Methods The levels of IL-2 in pleural fluid were measured by ELISA. MTT assay was used to detect the cytotoxicities against Lovo cell line of the TILs. Results The increase rate of TIL at the group with lower level of IL-2 was rapid than that of group with higher IL-2 level. The cytotoxicities against Lovo cell lines at the group with lower level of IL-2 were stronger than that of group with higher IL-2 level. Conclusion The level of IL-2 in pleural fluid relates to the increasing rate and cytotoxicity against tumor cells of the TILs. ReplaceFont
2003, 30(04): 278-279.
DOI: 10.3971/j.issn.1000-8578.2262
Abstract：
Objective To study the expression of FLIP in lung cancer and to investigate its clinical significance. Methods The immunohistochemical stain method was used to detect the expression of FLIP in tissue samples of 58 cases lung cancer and 16 benign lesions. The results were analyzed by HPIAS-1000. Results The positive rate of FLIP in lung cancer tissues was 80.03%(47/58), which was significantly higher than that in benign lesion tissues(P< 0.01).The expression level of FLIP was related to tumor stage,...
Objective To study the expression of FLIP in lung cancer and to investigate its clinical significance. Methods The immunohistochemical stain method was used to detect the expression of FLIP in tissue samples of 58 cases lung cancer and 16 benign lesions. The results were analyzed by HPIAS-1000. Results The positive rate of FLIP in lung cancer tissues was 80.03%(47/58), which was significantly higher than that in benign lesion tissues(P< 0.01).The expression level of FLIP was related to tumor stage,...
2003, 30(04): 280-281.
DOI: 10.3971/j.issn.1000-8578.3141
Abstract：
Objective To investigate effect on proliferation, cell cycle and expression of p21 and c-myc protein of human lung adenocarcinoma SLC-89 cells induced by Cisplatin in order to find out the mechanism of its anticancer action. Methods By techniques of cell culture in vitro, SLC-89 cells were treated by Cisplatin in different concentration for 72h, then proliferation of cell was measured by MTT method, and cell cycle and expression of p21 and c-myc protein were observed by Flow-Cytometry(FCM) respectively. R...
Objective To investigate effect on proliferation, cell cycle and expression of p21 and c-myc protein of human lung adenocarcinoma SLC-89 cells induced by Cisplatin in order to find out the mechanism of its anticancer action. Methods By techniques of cell culture in vitro, SLC-89 cells were treated by Cisplatin in different concentration for 72h, then proliferation of cell was measured by MTT method, and cell cycle and expression of p21 and c-myc protein were observed by Flow-Cytometry(FCM) respectively. R...
2003, 30(04): 282-284.
DOI: 10.3971/j.issn.1000-8578.2258
Abstract：
Objective To explore the relationship between expression of p16、PS2 and Resistance genes of GST-Pi、TOPOII、 PgP in breast cancer. Methods The detection and analysis of p16、PS2、GST-Pi、TOPOII、PgP genes proteins in 57 breast cancer were made by using the Instant Microwave heating-immunohistochistry technique. Results The positive expression rate of p16、PS2、GST-Pi、TOPOII、PgP are 36.84% 77.19%, 52.63%, 24.56%, 15.79%, respectively in breast cancer of 57 cases. Conclusion Abnorm...
Objective To explore the relationship between expression of p16、PS2 and Resistance genes of GST-Pi、TOPOII、 PgP in breast cancer. Methods The detection and analysis of p16、PS2、GST-Pi、TOPOII、PgP genes proteins in 57 breast cancer were made by using the Instant Microwave heating-immunohistochistry technique. Results The positive expression rate of p16、PS2、GST-Pi、TOPOII、PgP are 36.84% 77.19%, 52.63%, 24.56%, 15.79%, respectively in breast cancer of 57 cases. Conclusion Abnorm...
2003, 30(04): 285-287.
DOI: 10.3971/j.issn.1000-8578.2259
Abstract：
Objective To study the expression of matrix metalloproteinase-9 and matrix metalloproteinase-14 in endometriosis. Methods The expression of MMP-9 and MMP-14 in normal and ectopic endometrium was detected by the method of in situ hybridization. Results (1) MMP-14 were not detected in normal endometrium and it is only 20.0% positive rate in ectopic endometrium in endometriosis (P< 0.05). (2) MMP-9 were only detected in normal proliferate phase endometrium, and the positive rate was 6.9%, and it i...
Objective To study the expression of matrix metalloproteinase-9 and matrix metalloproteinase-14 in endometriosis. Methods The expression of MMP-9 and MMP-14 in normal and ectopic endometrium was detected by the method of in situ hybridization. Results (1) MMP-14 were not detected in normal endometrium and it is only 20.0% positive rate in ectopic endometrium in endometriosis (P< 0.05). (2) MMP-9 were only detected in normal proliferate phase endometrium, and the positive rate was 6.9%, and it i...
2003, 30(04): 288-290.
DOI: 10.3971/j.issn.1000-8578.2266
Abstract：
Objective To investigate the cell adhesion molecule E-cadherin and β-catenin expression and the significance in cervical cancer. Methods E-cadherin and β-catenin expression in 51 cases cervical cancer and corresponding lymph nodes were detected. Meanwhile, HPV16.18DNA of the secretion in cervical canal was examined. Results 31 cases showed negative expression of E-cad and so as 23 case of β-catenin. Loss expression in anyone was 37( 76.2%). Expression of E-cadherin and β-catenin in without lymph nodes ...
Objective To investigate the cell adhesion molecule E-cadherin and β-catenin expression and the significance in cervical cancer. Methods E-cadherin and β-catenin expression in 51 cases cervical cancer and corresponding lymph nodes were detected. Meanwhile, HPV16.18DNA of the secretion in cervical canal was examined. Results 31 cases showed negative expression of E-cad and so as 23 case of β-catenin. Loss expression in anyone was 37( 76.2%). Expression of E-cadherin and β-catenin in without lymph nodes ...
2003, 30(04): 291-293.
DOI: 10.3971/j.issn.1000-8578.2257
Abstract：
Objective To observe the effect of antiestrogen and antiprogestin on the proliferation of ovarian epithelial cancer (OEC) cell lines in vitro. Methods A variety of protocols were utilized to conduct this study. Results OEC cell line SKOV3 is ER(+)/PR(-), while OVCAR-3 is ER(+)/PR(+). High dose of tamxifen inhibited the proliferation of both cell lines, while mifepristone only inhibited OVCAR-3. Conclusion Antiestrogen and antiprogestin can inhibit the proliferation of some ovarian epithelial cancer cel...
Objective To observe the effect of antiestrogen and antiprogestin on the proliferation of ovarian epithelial cancer (OEC) cell lines in vitro. Methods A variety of protocols were utilized to conduct this study. Results OEC cell line SKOV3 is ER(+)/PR(-), while OVCAR-3 is ER(+)/PR(+). High dose of tamxifen inhibited the proliferation of both cell lines, while mifepristone only inhibited OVCAR-3. Conclusion Antiestrogen and antiprogestin can inhibit the proliferation of some ovarian epithelial cancer cel...
2003, 30(04): 294-295.
DOI: 10.3971/j.issn.1000-8578.2255
Abstract：
Objective To study the expression of p53 protein in ovarian cancer and its relationship to cell proliferative activity, lymph node metastasis as well as prognosis. Methods The expression of p53 and PCNA was detected in 68 cases of ovarian cancer by means of S -P immunohistochemical technique. Results 52.9% of ovarian cancer was positive. The cell porliferative activity and the frequency of lymph node metastasis in p53- positive cases were significantly higher than those of p53- negative (P< 0.05). Th...
Objective To study the expression of p53 protein in ovarian cancer and its relationship to cell proliferative activity, lymph node metastasis as well as prognosis. Methods The expression of p53 and PCNA was detected in 68 cases of ovarian cancer by means of S -P immunohistochemical technique. Results 52.9% of ovarian cancer was positive. The cell porliferative activity and the frequency of lymph node metastasis in p53- positive cases were significantly higher than those of p53- negative (P< 0.05). Th...
2003, 30(04): 296-297.
DOI: 10.3971/j.issn.1000-8578.2411
Abstract：
Objective To explore the feasibility of arsenic trioxide injected surrounding the tumor for the treatment of solid carcinoma from bladder. Methods Arsenic trioxide was injected intratumor after establishing ectopic bladder tumor.Pathologic examination of the tumor liver and kidney were performed also including the apopotosis of tumor cell. Results After treatment the lesion was reduced in size and weight. There was significant different between treat group and control group(P< 0.05). The apopotosis rat...
Objective To explore the feasibility of arsenic trioxide injected surrounding the tumor for the treatment of solid carcinoma from bladder. Methods Arsenic trioxide was injected intratumor after establishing ectopic bladder tumor.Pathologic examination of the tumor liver and kidney were performed also including the apopotosis of tumor cell. Results After treatment the lesion was reduced in size and weight. There was significant different between treat group and control group(P< 0.05). The apopotosis rat...
2003, 30(04): 298-299.
DOI: 10.3971/j.issn.1000-8578.2415
Abstract：
Objective To study significance the expression of the mutate p53 protein and bcl-2 gene in bladder carcinoma and peritumoral tissue. Methods Using SP method of immunohistochemically analyzed bladder carcinoma 58 cases. All of them are tested the expression of the mutant p53 protein and bcl-2 gene. Results The p53 positive rate was significantly correlated with the tumor grade and stage (P< 0.01). bcl-2 positive rate was different in superficial and invasive bladder cancer (P< 0.05). The expressio...
Objective To study significance the expression of the mutate p53 protein and bcl-2 gene in bladder carcinoma and peritumoral tissue. Methods Using SP method of immunohistochemically analyzed bladder carcinoma 58 cases. All of them are tested the expression of the mutant p53 protein and bcl-2 gene. Results The p53 positive rate was significantly correlated with the tumor grade and stage (P< 0.01). bcl-2 positive rate was different in superficial and invasive bladder cancer (P< 0.05). The expressio...
2003, 30(04): 301-303.
DOI: 10.3971/j.issn.1000-8578.2412
Abstract：
Objective To analyze the radiographic findings of the small bowel tumors and to evaluate the importance of the double contrast radiography. Methods 53 patients suffered from the small bowel tumors, in whom male 32, female 21, mean age 47 years old,were examined by double contrast radiography. The radiographic features of the small bowel tumors were reviewed. Results The largest lesion was 17×19cm,the smallest was 1× 1.2cm. The lesions were smaller than 6cm in 26 cases.The radiographic appearances of th...
Objective To analyze the radiographic findings of the small bowel tumors and to evaluate the importance of the double contrast radiography. Methods 53 patients suffered from the small bowel tumors, in whom male 32, female 21, mean age 47 years old,were examined by double contrast radiography. The radiographic features of the small bowel tumors were reviewed. Results The largest lesion was 17×19cm,the smallest was 1× 1.2cm. The lesions were smaller than 6cm in 26 cases.The radiographic appearances of th...
2003, 30(04): 304-306.
DOI: 10.3971/j.issn.1000-8578.2252
Abstract：
Objective To determine the utility and accuracy of fine needle aspiration cytology(FNAC) as well as its sensitivity,specificity and predictive value in the diagnosis of breast masses. Methods Data on breast masses with 1115 case FNAC done were retrieved from the records of the cytopathology laboratory. Results Histopathology was available in 328/1115.The overall accuracy of diagnosis were 96.3%,the false negative rate, potential false positive rate and overall nisdiagnositic rate were 4.8%, 1.7% and ...
Objective To determine the utility and accuracy of fine needle aspiration cytology(FNAC) as well as its sensitivity,specificity and predictive value in the diagnosis of breast masses. Methods Data on breast masses with 1115 case FNAC done were retrieved from the records of the cytopathology laboratory. Results Histopathology was available in 328/1115.The overall accuracy of diagnosis were 96.3%,the false negative rate, potential false positive rate and overall nisdiagnositic rate were 4.8%, 1.7% and ...
2003, 30(04): 307-308.
DOI: 10.3971/j.issn.1000-8578.2253
Abstract：
Objective To explore the apply value of DSA techniques in bilateral uterine arteries embolization(UAE) of treating fibroid. Methods 15 cases of fibroid were treated by uterine arteries embolization. After a 5F Yashiro catheter was placed into uterine arteries, silk fragment and gelfoam powder was inserted to obstruct the blood supply of fibroid. Many kinds of DSA techniques were performed in the operation. Results Success rate of operation was 100%.The mean operation time was 60.5± 15.1 minutes and mean...
Objective To explore the apply value of DSA techniques in bilateral uterine arteries embolization(UAE) of treating fibroid. Methods 15 cases of fibroid were treated by uterine arteries embolization. After a 5F Yashiro catheter was placed into uterine arteries, silk fragment and gelfoam powder was inserted to obstruct the blood supply of fibroid. Many kinds of DSA techniques were performed in the operation. Results Success rate of operation was 100%.The mean operation time was 60.5± 15.1 minutes and mean...
2003, 30(04): 309-310.
DOI: 10.3971/j.issn.1000-8578.2250
Abstract：
Objective To study the effects of Utilin“s” liquor on synthesis treatment the malignant tumors. Methods 133 cases with malignant tumors were treated with Utilin“s” liquor combining with chemotherapy or only chemotherapy. And to observed the results of treatment,living rate of one year,living quality and immune functions. Results The remission rate and one year s living rate of the trial group was separately 61.76% and 57.35%. and significantly higher...
Objective To study the effects of Utilin“s” liquor on synthesis treatment the malignant tumors. Methods 133 cases with malignant tumors were treated with Utilin“s” liquor combining with chemotherapy or only chemotherapy. And to observed the results of treatment,living rate of one year,living quality and immune functions. Results The remission rate and one year s living rate of the trial group was separately 61.76% and 57.35%. and significantly higher...
2003, 30(04): 311-312.
DOI: 10.3971/j.issn.1000-8578.2251
Abstract：
Objective To observe the effect and toxicity of IPED regimen in treatment of refractory Non-Hodgkin s Lymphoma. Methods All 21 patients were treated over two cycles with IPED regimen. The IPED regimen was repeated every 28 days. The therapeutic effect was observed after treatment. Results 5 patients achieved complete remission(CR), 10 partial remission(PR) 3 stable disease(SD),3 progression disease(PD). The overall response rate was 71.4%.The main side effects were myelosuppression and gastrointest...
Objective To observe the effect and toxicity of IPED regimen in treatment of refractory Non-Hodgkin s Lymphoma. Methods All 21 patients were treated over two cycles with IPED regimen. The IPED regimen was repeated every 28 days. The therapeutic effect was observed after treatment. Results 5 patients achieved complete remission(CR), 10 partial remission(PR) 3 stable disease(SD),3 progression disease(PD). The overall response rate was 71.4%.The main side effects were myelosuppression and gastrointest...
2003, 30(04): 313-315.
DOI: 10.3971/j.issn.1000-8578.2248
Abstract：
Objective To observe the changes of interleukin 8(IL-8),interleukin 10 (IL-10) and glitathione S-transferases(GST) of patients undergoing gastric cardiac cancer radial surgery by propofol and thiopentone. Methods Forty patients undergoing cardiac radical surgery were divided into group P (propofol) and group T (thiopentone), the contents of IL-8, IL-10 and activity of GST in blood samples were measured. Results The contents of IL-8, IL-10 and the activity of GST were higher than that of 5 minutes before an...
Objective To observe the changes of interleukin 8(IL-8),interleukin 10 (IL-10) and glitathione S-transferases(GST) of patients undergoing gastric cardiac cancer radial surgery by propofol and thiopentone. Methods Forty patients undergoing cardiac radical surgery were divided into group P (propofol) and group T (thiopentone), the contents of IL-8, IL-10 and activity of GST in blood samples were measured. Results The contents of IL-8, IL-10 and the activity of GST were higher than that of 5 minutes before an...
2003, 30(04): 316-317.
DOI: 10.3971/j.issn.1000-8578.2249
Abstract：
Objective To investigate the application of neuroendoscope in the pituitary surgery. Methods 26 patients with pituitary adenomas were surgical treated through a nostril using rigid endoscopes. 14 patients had hormone-secreting adenomas(7 with prolactinomas, 4 with grouth hormone-secreting adenomas and 3 with Cushing s disease), 12 patients had nonsecreting adenomas. Results 22 underwent total resection and 4 subtotal resection, rapid improvement of vision was noted postoperatively. Among the 14 patients w...
Objective To investigate the application of neuroendoscope in the pituitary surgery. Methods 26 patients with pituitary adenomas were surgical treated through a nostril using rigid endoscopes. 14 patients had hormone-secreting adenomas(7 with prolactinomas, 4 with grouth hormone-secreting adenomas and 3 with Cushing s disease), 12 patients had nonsecreting adenomas. Results 22 underwent total resection and 4 subtotal resection, rapid improvement of vision was noted postoperatively. Among the 14 patients w...
2003, 30(04): 318-319.
DOI: 10.3971/j.issn.1000-8578.2246
Abstract：
Objective Discuss the indication of the exploratory thoracotomy for cancer patients. Methods Compare and analyze the conditions observed in operations with iconography. Results Among the 21 patients of whom the contact diameter between the tumor and mediastinum on the CT photograph is larger than 3 centimeters, there are 19 of them whose hilums display frozen state in operations; 23 out of the 24 patients with disappeared mediastinal fat pad are unable to be executed dissection of hilum vessel and bronchus...
Objective Discuss the indication of the exploratory thoracotomy for cancer patients. Methods Compare and analyze the conditions observed in operations with iconography. Results Among the 21 patients of whom the contact diameter between the tumor and mediastinum on the CT photograph is larger than 3 centimeters, there are 19 of them whose hilums display frozen state in operations; 23 out of the 24 patients with disappeared mediastinal fat pad are unable to be executed dissection of hilum vessel and bronchus...
2003, 30(04): 320-321.
DOI: 10.3971/j.issn.1000-8578.2247
Abstract：
Objective To study problems regarding to reoperation of thyroid carcinoma. Methods 108 cases with thyroid carcinoma(from 1989 to 2002) were summarized retrospectively for their condition of reoperation. Results 108 cases with thyroid carcinoma had been reoperated for 112 times.Complications occurred in 22% of the cases.Patients were followed-up for 2～13 years, 5 and 10 years survival rate were 75.0%(81/108) and 37%(40/108) respectively. Conclusion On time examine a patient, the surgical operation method ...
Objective To study problems regarding to reoperation of thyroid carcinoma. Methods 108 cases with thyroid carcinoma(from 1989 to 2002) were summarized retrospectively for their condition of reoperation. Results 108 cases with thyroid carcinoma had been reoperated for 112 times.Complications occurred in 22% of the cases.Patients were followed-up for 2～13 years, 5 and 10 years survival rate were 75.0%(81/108) and 37%(40/108) respectively. Conclusion On time examine a patient, the surgical operation method ...
2003, 30(04): 322-323.
DOI: 10.3971/j.issn.1000-8578.1410
Abstract：
Objective To explore the reason.treatment and prevention of Stoma fistula of rectum after TME(total mesorectal excision). Methods TO Analyze 254 cases which were treated by TME whose anastomose fistula were put out of peritoneum retrospectively. Results Among 254 cases there are 29 cases had stoma fistula,the rate is 11.4%. and they have been recovered through conserve treatment such as local stapling and taking food. Conclusion The concidence rate of TME is higher,and have relationship with blood suppl...
Objective To explore the reason.treatment and prevention of Stoma fistula of rectum after TME(total mesorectal excision). Methods TO Analyze 254 cases which were treated by TME whose anastomose fistula were put out of peritoneum retrospectively. Results Among 254 cases there are 29 cases had stoma fistula,the rate is 11.4%. and they have been recovered through conserve treatment such as local stapling and taking food. Conclusion The concidence rate of TME is higher,and have relationship with blood suppl...
2003, 30(04): 324-325.
DOI: 10.3971/j.issn.1000-8578.1411
Abstract：
Objective To investigate the effect of radiotherapy and adverse reaction on skin transplant after operation of keloid. Methods 40 patients with skin transplant after operation of keloid were retrospectively analyzed. They were divided into two groups based on irradiation dose:group A 600～ 1?000cGy/f,every other day or single irradiation,D T 1?000～ 1?800cGy; group B 200～300 cGy/f,irradiated every other day,D T 1?000～ 2?000cGy. Results The recurrence of group A was(4/22) 18%;the recurrence of group B ...
Objective To investigate the effect of radiotherapy and adverse reaction on skin transplant after operation of keloid. Methods 40 patients with skin transplant after operation of keloid were retrospectively analyzed. They were divided into two groups based on irradiation dose:group A 600～ 1?000cGy/f,every other day or single irradiation,D T 1?000～ 1?800cGy; group B 200～300 cGy/f,irradiated every other day,D T 1?000～ 2?000cGy. Results The recurrence of group A was(4/22) 18%;the recurrence of group B ...
2003, 30(04): 326-327.
DOI: 10.3971/j.issn.1000-8578.1412
Abstract：
Objective To analyse 60 patients of tongue cancer with different therapy in order to discuss the best therapy style. Methods Reviewing 60 patients from July,1975 through July,1994, 25 patients were treated by simple radiotherapy, 10 patients with pre-surgery radiotherapy and 25 patients with post-surgery radiotherapy. Results The total 3- and 5-year survival rates were 58.3% (35/60)and 46.7% (28/60), while those of stage Ⅰ,Ⅱ,Ⅲ,and Ⅳ were 80.0%, 60.0%, 60.0%, 45.5% and 70.0%, 40,0%, 46.7%, ...
Objective To analyse 60 patients of tongue cancer with different therapy in order to discuss the best therapy style. Methods Reviewing 60 patients from July,1975 through July,1994, 25 patients were treated by simple radiotherapy, 10 patients with pre-surgery radiotherapy and 25 patients with post-surgery radiotherapy. Results The total 3- and 5-year survival rates were 58.3% (35/60)and 46.7% (28/60), while those of stage Ⅰ,Ⅱ,Ⅲ,and Ⅳ were 80.0%, 60.0%, 60.0%, 45.5% and 70.0%, 40,0%, 46.7%, ...
2003, 30(04): 328-330.
DOI: 10.3971/j.issn.1000-8578.1413
Abstract：
Objective To study the diagnosis and treatment of single-cell type and one-sided nonseminnoma. Methods It was studied on retrospection of 45 patients of single-cell type and one-sided nonseminnoma. Results The 5-year survival was 66.7% for stage Ⅰ, 33.3% for stageⅡ,0 for stage Ⅲ. The 5-year survival was 38.5% for the patients with fine-needle aspiration biopsy and 65.2% for the others with not; In stage Ⅰ patients, the 5-year survival was 57.1% for embryonal carcinoma and 80% for teratoma; there was...
Objective To study the diagnosis and treatment of single-cell type and one-sided nonseminnoma. Methods It was studied on retrospection of 45 patients of single-cell type and one-sided nonseminnoma. Results The 5-year survival was 66.7% for stage Ⅰ, 33.3% for stageⅡ,0 for stage Ⅲ. The 5-year survival was 38.5% for the patients with fine-needle aspiration biopsy and 65.2% for the others with not; In stage Ⅰ patients, the 5-year survival was 57.1% for embryonal carcinoma and 80% for teratoma; there was...
