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LANG Zhongliang, WANG Minggang. Prognostic Value of Completion Lymph Node Dissection on Melanoma Patients with Positive Sentinel Lymph Node Biopsy: A Meta-analysis[J]. Cancer Research on Prevention and Treatment, 2018, 45(5): 311-315. DOI: 10.3971/j.issn.1000-8578.2018.17.0955
Citation: LANG Zhongliang, WANG Minggang. Prognostic Value of Completion Lymph Node Dissection on Melanoma Patients with Positive Sentinel Lymph Node Biopsy: A Meta-analysis[J]. Cancer Research on Prevention and Treatment, 2018, 45(5): 311-315. DOI: 10.3971/j.issn.1000-8578.2018.17.0955

Prognostic Value of Completion Lymph Node Dissection on Melanoma Patients with Positive Sentinel Lymph Node Biopsy: A Meta-analysis

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  • Corresponding author:

    WANG Minggang, E-mail: mgwang1105@sina.com

  • Received Date: October 12, 2017
  • Revised Date: January 08, 2018
  • Available Online: January 12, 2024
  • Objective 

    To assess the prognostic value of completion lymph node dissection on melanoma patients with positive sentinel lymph node biopsy.

    Methods 

    We searched PubMed, Embase, Cochrane Library, CNKI, Wanfang and the reference trace for relevant literature. Meta-analysis was applied for patients' survival.

    Results 

    A total of 10 clinical trials were included. There was no significant difference between the completion lymph node dissection group and the lymph node observation group in melanoma specific survival (HR: 0.99, 95%CI: 0.86-1.14, P=0.89), recurrence-free survival (HR: 0.89, 95%CI: 0.72-1.08, P=0.24) or distant metastasis-free survival (HR: 1.03, 95%CI: 0.89-1.20, P=0.71).

    Conclusion 

    Completion lymph node dissection could not benefit the survival of melanoma patients with positive sentinel lymph node biopsy.

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