Advanced Search
YU Yuanjie, ZHAO Liang, CHEN Jihong, SHEN Qianni, TAN Shiyun, LUO Hesheng. Value of Double-Balloon Enteroscopy in Diagnosing Alimentary Tract Hemorrhage Induced by Stromal Tumor of Small Bowel[J]. Cancer Research on Prevention and Treatment, 2015, 42(02): 177-180. DOI: 10.3971/j.issn.1000-8578.2015.02.017
Citation: YU Yuanjie, ZHAO Liang, CHEN Jihong, SHEN Qianni, TAN Shiyun, LUO Hesheng. Value of Double-Balloon Enteroscopy in Diagnosing Alimentary Tract Hemorrhage Induced by Stromal Tumor of Small Bowel[J]. Cancer Research on Prevention and Treatment, 2015, 42(02): 177-180. DOI: 10.3971/j.issn.1000-8578.2015.02.017
shu

Value of Double-Balloon Enteroscopy in Diagnosing Alimentary Tract Hemorrhage Induced by Stromal Tumor of Small Bowel

  • Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060,China

More Information
  • Received Date: May 08, 2014
  • Revised Date: September 29, 2014
    Graphical Abstract
    • Abstract
  • Objective To investigate the diagnostic value of double balloon enteroscopy(DBE) in diagnosing alimentary tract hemorrhage induced by stromal tumor of small bowel(STSB) and analyze the morphological features of small bowel under endoscopy. Methods We retrospectively analyzed the clinical manifestation, endoscopic appearance, tumor size, location, imageological characteristics and postoperative pathological diagnosis data of 40 patients with alimentary tract hemorrhage induced by STSB. Results Alimentary tract hemorrhage induced by STSB was more common in the elderly [(50.50±10.21) year-old) ], with melena, bloody stool or positive in occult test as the main characteristics, and mostly suffered from anemia, abdominal pain, distension and loss of body weight. Lesion was detected by abdomen CT or angiography prior to DBE in 15.00% (6/40) of patients; 95.00% (38/40) stromal tumor of small intestine was detected by DBE; 5.00%(2/40) of the patients was missed diagnosis. Stromal tumor appeared as hard, spherical or hemispherical submucosal protrusion with clearly demarcated borders. The mucosal was intact or of superficial erosion, with part of luminal narrowing. Risk factors were defined after the operation: very low risk (6 cases), low risk (15 cases), intermediate risk (13 cases) and high risk (6 cases). Conclusion DBE is an effective and safe method for identifying STSB, however, it still has limitations in evaluating the invasion risk and clinical prognosis. For early detection, accurate clinical evaluation and prognosis of STSB combined with other diagnostic information, further studies will be needed.
    • FullText(HTML)
    • References (16)
  • [1]
    Joensuu H, Hohenberger P, Corless CL. Gastrointestinal stromal tumour[J]. Lancet, 2013, 382(9896): 973-83.
    [2]
    Raju GS, Gerson L, Das A, et al. American Gastroenterological Association (AGA) Institute technical review on obscure gastrointestinal bleeding[J]. Gastroenterology, 2007, 133(5): 16 97-717.
    [3]
    Yamamoto H, Sekine Y, Sato Y, et al. Total enteroscopy with a nonsurgical steerable double-balloon method[J]. Gastrointest Endosc, 2001, 53(2): 216-20.
    [4]
    Miettinen M, Lasota J. Histopathology of gastrointestinal stromal tumor[J]. J Surg Oncol, 2011, 104(8): 865-73.
    [5]
    Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor[J]. Hum Pathol, 2008, 39(10): 14 11-9.
    [6]
    Miettinen M, El-Rifai W, H L Sobin L, et al. Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review[J]. Hum Pathol, 2002, 33(5): 478-83.
    [7]
    Hasegawa T, Matsuno Y, Shimoda T, et al. Gastrointestinal stromal tumor: consistent CD117 immunostaining for diagnosis, and prognostic classification based on tumor size and MIB-1 grade[J]. Hum Pathol, 2002, 33(6): 669-76.
    [8]
    Pidhorecky I, Cheney RT, Kraybill WG, et al. Gastrointestinal stromal tumors: current diagnosis, biologic behavior, and management[J]. Ann Surg Oncol, 2000, 7(9): 705-12.
    [9]
    Levy AD, Remotti HE, Thompson WM, et al. Gastrointestinal stromal tumors: radiologic features with pathologic correlation[J]. Radiographics, 2003, 23(2): 283-304, 456.
    [10]
    Grover S, Ashley SW, Raut CP. Small intestine gastrointestinal stromal tumors[J]. Curr Opin Gastroenterol, 2012, 28(2): 113-23.
    [11]
    Nishimura M, Yamamoto H, Kita H, et al. Gastrointestinal stromal tumor in the jejunum: diagnosis and control of bleeding with electrocoagulation by using double-balloon enteroscopy[J]. J Gastroenterol, 2004, 39(10): 1001-4.
    [12]
    Sandrasegaran K, Rajesh A, Rushing DA, et al. Gastrointestinal stromal tumors: CT and MRI findings[J]. Eur Radiol, 2005, 15(7): 14 07-14.
    [13]
    Kameda N, Higuchi K, Shiba M, et al. A prospective, single-blind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding[J]. J Gastroenterol, 2008, 43(6): 434-40.
    [14]
    Marmo R, Rotondano G, Casetti T, et al. Degree of concordance between double-balloon enteroscopy and capsule endoscopy in obscure gastrointestinal bleeding: a multicenter study[J]. Endoscopy, 2009, 1(7): 587-92.
    [15]
    Dematteo RP, Lewis JJ, Leung D, et al. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival[J]. Ann Surg, 2000, 231(1): 51-8.
    [16]
    Patil DT, Rubin BP. Gastrointestinal stromal tumor: advances in diagnosis and management[J]. Arch Pathol Lab Med, 2011, 13 5(10): 1298-310.
    • Related Articles

  • Related Articles

    [1]JIANG Yang, YU Huizhi, GAO Ya, SHEN Yu, MAO Min, LIU Chongmei. AI Cytomorphology Combined with DNA-image Cytometry for Identifying Benign and Malignant Pleural Effusion and Ascites[J]. Cancer Research on Prevention and Treatment, 2023, 50(4): 390-396. DOI: 10.3971/j.issn.1000-8578.2023.22.0762
    [2]XU Yijun, ZHU Mingchen. Diagnostic Value of cfDNA in Pancreatic Cancer[J]. Cancer Research on Prevention and Treatment, 2022, 49(12): 1265-1268. DOI: 10.3971/j.issn.1000-8578.2022.22.0699
    [3]ZHANG Peng, GAO Min, FENG Feifei, LI Mengyuan, LIU Jinyan, HUANG Lingling. Diagnostic Value of Serum LncRNAs for Bone Metastasis in Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2022, 49(6): 593-598. DOI: 10.3971/j.issn.1000-8578.2022.21.1047
    [4]ZHANG Jia, TAO Haibo, DING Yingying, LI Mei, SUN Shiyun, LI Manzhu, LI Kun. Diagnostic Value of mDIXON Quant MRI for Vertebral Metastasis[J]. Cancer Research on Prevention and Treatment, 2021, 48(9): 888-892. DOI: 10.3971/j.issn.1000-8578.2021.21.0193
    [5]FENG Yiming, YAO Desheng, LU Yan, LONG Ying, WU Guangteng, DONG Tingting, XU Xun. Expression of Serum miR-1246 in Patients with Cervical Squamous Cell Carcinoma and Its Clinical Significance[J]. Cancer Research on Prevention and Treatment, 2019, 46(6): 532-536. DOI: 10.3971/j.issn.1000-8578.2019.18.1727
    [6]ZHOU Lin, ZENG Lei. Qualitative Diagnostic Value of Different Apparent Diffusion Coefficients on Metastatic Pelvic Lymph Nodes in Prostate Cancer[J]. Cancer Research on Prevention and Treatment, 2019, 46(3): 248-252. DOI: 10.3971/j.issn.1000-8578.2019.18.1393
    [7]Luo Zhaoqin, Zhao Bingbing, Zhang Wei, Wang Qi, Pan Zhongmian, Yang Zhijun, Li Li. Diagnostic Value of Serum HE4 in Ovarian Tumor[J]. Cancer Research on Prevention and Treatment, 2012, 39(03): 312-317. DOI: 10.3971/j.issn.1000-8578.2012.03.017
    [8]WANG Ai-ying. The value of the small bowel tumors in the diagnosis of double contrast radiography[J]. Cancer Research on Prevention and Treatment, 2003, 30(04): 301-303. DOI: 10.3971/j.issn.1000-8578.2412
    [9]Chen Guoquan, . The Diagnostic Value of the Carbohydrate Antigen CA50 on the Malignant Tumors[J]. Cancer Research on Prevention and Treatment, 1995, 22(6): 357-358.
    [10]Xu Guoben, . A Study of Diagnostic Value of SLSEPs in Intracranial Tumors[J]. Cancer Research on Prevention and Treatment, 1994, 21(4): 218-220.

Catalog

    Get Citation
    PDF
    XML
    Article views (1477) PDF downloads (476) Cited by()
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles

    Contact Us

    Address：116 Zhuodaoquan South Road,
    Hongshan District, Wuhan（430079）

    Tel：027－87670126

    Email：zlfzyjzz@vip.163.com

    This work is licensed under a Creative Commons Attribution 3.0 License.

    Email Alert RSS
    Total visits：18750428 Visits today：10071

    Copyright © Editorial Department of Cancer Prevention Research 鄂公网安备 42011102005013号 鄂ICP备2022015867号

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return