| Citation: |
ZHANG Jia, TAO Haibo, DING Yingying, LI Mei, SUN Shiyun, LI Manzhu, LI Kun. Diagnostic Value of mDIXON Quant MRI for Vertebral Metastasis[J]. Cancer Research on Prevention and Treatment, 2021, 48(9): 888-892. DOI: 10.3971/j.issn.1000-8578.2021.21.0193
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To evaluate the diagnostic efficacy of mDIXON Quant for vertebral metastasis.
We retrospectively analyzed MRI images of 152 patients with clinically diagnosed malignant tumors and vertebral metastases. Scanning sequence included T1WI, STIR, mDIXON Quant and enhanced T1WI. We compared the diagnostic efficiency between T1WI and FF images for vertebral metastases. FF values between normal vertebral body and vertebral metastases were quantitatively compared, and the diagnostic efficacy of FF value was evaluated by ROC curve.
The sensitivity, false positive rate, false negative rate, negative predictive value and accuracy of FF images in the diagnosis of vertebral metastases were all higher than those of T1WI images. The FF value of vertebral metastasis was significantly lower than that of normal vertebral body (Z=-21.792, P < 0.05), and the area under ROC curve was 0.987 and the cutoff value was 9.87%. The diagnostic sensitivity and specificity of vertebral metastasis were 99.6% and 92.0%.
mDIXON Quant can quantitatively determine the fat content of vertebral metastasis and has a high diagnostic efficiency for vertebral metastases.
Competing interests: The authors declare that they have no competing interests.
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