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WANG Shu-min, MA Ying-yan, LIU Kun. Preliminary Study on Lung Cancer Cell Apoptosis lnduced by Arsenic Trioxide ln vitro[J]. Cancer Research on Prevention and Treatment, 2001, 28(04): 287-288. DOI: 10.3971/j.issn.1000-8578.1762
Citation: WANG Shu-min, MA Ying-yan, LIU Kun. Preliminary Study on Lung Cancer Cell Apoptosis lnduced by Arsenic Trioxide ln vitro[J]. Cancer Research on Prevention and Treatment, 2001, 28(04): 287-288. DOI: 10.3971/j.issn.1000-8578.1762
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Preliminary Study on Lung Cancer Cell Apoptosis lnduced by Arsenic Trioxide ln vitro

  • The General Hospital of Shenyang, PlA, Shenyang 110015, China

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  • Received Date: March 23, 2000
  • Revised Date: April 15, 2001
    Abstract
  • Objective To study whether arsenic trioxide (As2 O3 )will induce apoptosis of lung cancer cells. Methods Apoptosis rate and morphologic changes of A549 cells induced by As 2O 3 were observed under the microscope?fluorescence microscope. Results apoptosis rate induced by As 2O 3 of 1?2.5μmol/L was 22.80%,30.15% at 24h;41.75%,60.04% at 48 h and 56.38%,73.70% at 72 h,respectively,they were all higher than those acted by 5 Fu.Typical apoptotic cells were seen that the bodies of the cells became smaller an...
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    LIU Kun

    • The General Hospital of Shenyang, PlA, Shenyang 110015, China

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