Correlation Study of Spontaneous Apoptosis and Ki-67 Immunoreactivity inMeningiomas

Objective To investigate the inter relationship between spontaneous apoptosis and proliferative activity in benign,atypical and malignant meningiomas. Methods 40 meningiomas of diverse histological subtypes and grades were investigated apoptosis index(AI) with terminal deoxynuleotidy 1 transferase mediated dUTP biotin nick end labeling(TUNEL) as well as immunohistochemical analysis of Ki 67. Results The apoptosis index were significantly higher in high grade meningiomas than in benign meningiomas (P<...