Advanced Search
WANG Xiao-li, CHEN Jin-hua, GONG Xing-mu. Expression and Significance of EphA2 and VEGF in Non-small Cell Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2007, 34(05): 334-336. DOI: 10.3971/j.issn.1000-8578.2202
Citation: WANG Xiao-li, CHEN Jin-hua, GONG Xing-mu. Expression and Significance of EphA2 and VEGF in Non-small Cell Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2007, 34(05): 334-336. DOI: 10.3971/j.issn.1000-8578.2202
shu

Expression and Significance of EphA2 and VEGF in Non-small Cell Lung Cancer

  • Medical College of Jishou University, Jishou 416000, China

More Information
  • Corresponding author:

    CHEN Jin-hua

  • Received Date: May 14, 2006
  • Revised Date: December 14, 2006
    Abstract
  • Objective 　To investigate the expression of EphA2 and VEGF in NSCLC and its significance. Methods 　The expression levels of EphA2 and VEGF were determined by immunohistochemical analysis in 63 cases of NSCLC. Results 　The expression of EphA2 and VEGF were significantly higher in NSCLC. EphA2 levels did not appear to relate to histological type or differentiation but did relate to clinical stage and metastases. Tumor differentiation, lymph node metastasis and clinical stage correlated with the expression of VEGF. EphA2 level positively correlated with VEGF level. Conclusion 　These data suggest that EphA2 may provide a molecular maker to identify and predict patient s who have isolated brain metastases. Moreover, the high levels of EphA2 and VEGF in NSCLC may provide an opportunity for therapeutic targeting.
    • FullText(HTML)
    • References (0)
    • Related Articles

  • Related Articles

    [1]Miao-zi GONG, Hui-ying HE. Advances in Immunohistochemical Detection of Biomarkers for Urothelial Carcinoma[J]. Cancer Research on Prevention and Treatment. DOI: 10.3971/j.issn.1000-8578.2025.25.0282
    [2]ZHAO Hongyu, ZENG Liang. Advances in Immunohistochemical Markers in Molecular Classification of Medulloblastoma[J]. Cancer Research on Prevention and Treatment, 2018, 45(4): 247-252. DOI: 10.3971/j.issn.1000-8578.2018.17.1186
    [3]WANG Xiao-li, WAN Yi-xin, ZHANG Qi-kun. Expression and Significance of HIF-1αand VEGF in Non-small Cell Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2005, 32(08): 487-489. DOI: 10.3971/j.issn.1000-8578.1808
    [4]WANG Li-mei, LI Li, ZHANG Wei, et al, . Relationship between the vascular endothelial growth factor and microvessel density of ovarian neoplasm and its clinic-pathology[J]. Cancer Research on Prevention and Treatment, 2003, 30(02): 88-91. DOI: 10.3971/j.issn.1000-8578.75
    [5]WU Kai-song, LIU Ming-qiu. Relationship of vascular endothelial factor and microvessel density in non-small cell lung cancer tissue[J]. Cancer Research on Prevention and Treatment, 2002, 29(02): 126-127. DOI: 10.3971/j.issn.1000-8578.936
    [6]CAO Jun, GAO Ping, HUANG Ying-gui, et al. The Clinicopathological and Immunohistochemical Study of Oifactory Neuroblatoma[J]. Cancer Research on Prevention and Treatment, 2000, 27(06): 441-443. DOI: 10.3971/j.issn.1000-8578.1208
    [7]CHEN Chun-mei, XIA He-shun, WU Chang-ming. Pathology and Immunohistochemical Study of Mucous Malignant Melanoma[J]. Cancer Research on Prevention and Treatment, 2000, 27(05): 378-379. DOI: 10.3971/j.issn.1000-8578.2754
    [8]LIU Du-hu, ZHANG Xue-yong, HUANG Yu-xin. The Correlation between the Expression of Vascular Endothelial Growth Factor and Its Receptor KDR and Angiogenesis in Human Gastric Carcinoma[J]. Cancer Research on Prevention and Treatment, 1999, 26(5): 350-357.
    [9]Liu Yunchu, . Immunohistochemical Study of Transforming Growth Factor-β2 in Prostatic Cancer[J]. Cancer Research on Prevention and Treatment, 1998, 25(4): 276-278.
    [10]J. F. Wang, . Immunohistochemical Study of Colonic Carcinoma[J]. Cancer Research on Prevention and Treatment, 1995, 22(6): 347-349.

Catalog

    GONG Xing-mu

    • Medical College of Jishou University, Jishou 416000, China

    1. On this Site
    2. On Google Scholar
    3. On PubMed
    Get Citation
    PDF
    XML
    Article views (3001) PDF downloads (890) Cited by()
    Turn off MathJax
    Article Contents
    Abstract
    Related Articles

    Download Center

    Links

    Contact Us

    Address：116 Zhuodaoquan South Road,
    Hongshan District, Wuhan（430079）

    Tel：027－87670126

    Email：zlfzyjzz@vip.163.com

    This work is licensed under a Creative Commons Attribution 3.0 License.

    Email Alert RSS
    Total visits：22070731 Visits today：36380

    Copyright © Editorial Department of Cancer Prevention Research 鄂公网安备 42011102005013号 鄂ICP备2022015867号

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return