化学致癌物质BBN的制备及其诱发大鼠膀胱肿瘤的作用
PREPARATION OF CHEMICAL CARCINOGEN BBN AND ITS INDLICTION OF BLADDER TUMOR IN RATS
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摘要: 我们制备N—丁基—N—(4—羟基丁基)—亚硝胺(BBN)，并用于诱发大鼠膀胱肿瘤，获得成功。Abstract: N-Butyl-N-(4-hydroxy-butyl)-nitrosamine(BBN)was prepared in Our laboratory, and we have Succeeded Success-fully to induce bladder tumor inrats with this nitrosoamine.
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1. 范贤骏、谢建国等中华肿瘤杂志.3(1):181-183,1986. 2. 范贤骏、谢建国等实用癌症杂志(1):1-3,1987 3. Syntheses of N-Alkyl-N-(hydroxy-oroYO-alkyl) itrosamints related to N-Butyl-N-(4-hydroxybutyl) hitroamine, a Potent Bladder Carcinogen. Chem, pharm, Bull, 26(12)3891-3896 1978 4. Inhibitim of N-n-Butyl-N-(4-yaroybutyt) aitrosamine-induced UrinaryBladder Cancer in Rats by. Aamiuisration of Diulfiram in the Diet. Cancer Res.39,3040-3043,1979. 5. 石炳毅等中华病理学杂志6(4):295,1987
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