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腹腔化疗治疗复发及转移性宫颈癌的近期疗效

蒋兆香, 阎福华, 赵新霞

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蒋兆香, 阎福华, 赵新霞. 腹腔化疗治疗复发及转移性宫颈癌的近期疗效[J]. 肿瘤防治研究, 1999, 26(4): 299-300.
引用本文: 蒋兆香, 阎福华, 赵新霞. 腹腔化疗治疗复发及转移性宫颈癌的近期疗效[J]. 肿瘤防治研究, 1999, 26(4): 299-300.
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JIANG Zhao-xiang, YAN Fu-hua, ZHAO Xin-xia. The Effect of Intraperitoneal Chemotherapy in Recurrence and Metastasis Carcinoma of the Cervix[J]. Cancer Research on Prevention and Treatment, 1999, 26(4): 299-300.
Citation: JIANG Zhao-xiang, YAN Fu-hua, ZHAO Xin-xia. The Effect of Intraperitoneal Chemotherapy in Recurrence and Metastasis Carcinoma of the Cervix[J]. Cancer Research on Prevention and Treatment, 1999, 26(4): 299-300.
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腹腔化疗治疗复发及转移性宫颈癌的近期疗效

  • 1. 湖北省肿瘤医院, 武汉 430079;2. 河南省洛阳市第二中医院

The Effect of Intraperitoneal Chemotherapy in Recurrence and Metastasis Carcinoma of the Cervix

  • Hubei Provincial Cancer Hospital, Wuhan 430079

摘要

    摘要
  • 摘要: 方法: 本文对20例宫颈癌复发及转移接受大剂量DDP腹腔化疗, 并与19例综合治疗病例比较近期疗效。结果: 有效率分别为95 %及42.1 %。经统计学处理, 有极显著性差异(P<0.001)。结论: 腹腔化疗对于宫颈癌复发及转移不失为一种有效的新途径。
    Abstract: Objective： To explore a new effective regimen for recurrence and distal metasasis carcinoma of the cervix. Methods：Twenty patients with local recurrence and/or distal metastasis carcinoma of the cervix received intraperitoneal chemotherapy were studied. All patients were treated with DDP, 150 mg/m2. The cycle was repeated every 21 days. All patients were evaluable for response. Results： Compared with the other two methods, the tumour shrank obviously after intraperitoned chemotherapy (P<0.001). None of these patients occured serious complication. Conclusion：Our study indicated that intraperitoneal chemotherapy is a effective way for local recurrence and distal metasis carcinoma of the cervix.
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    • 参考文献(12)
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    [2] 全国肿瘤防治研究办公室, 中国抗癌协会合编.中国常见恶性肿瘤诊治规范.第七分册. 1990: 10;
    [3] GEOFFREY R.WEISS, M .D., etal. A Phase II Trial of Cisplatin and 5-Fluorouracil with Allopurinol for Recurrent o rMetastatic carcinoma of the Uterine Cervix: A Southwest Oncology Group Trial. Gynecol Oncol, 1990, 37, 354-358;
    [4] NADER HUSSEINZADEH, PHZLIP SHRAKE, etal. Chemotherapy and Extended-Field Radiation Therapy to Para-aortic Area in Patients with Histologically Prover Metastatic Cervical Cancer to Para-aortic Nodes: A Phase II Pilot study. Gynecol Oncol, 1994, 52, 326-331;
    [5] Shafika .M.D .Anal Submucosal injection: A new route for drug administration in pelvic malignancies IV, Submucosal anal injection in the treatment of cancer of uterrine cervix-Preliminary study. Am j OBSTET GYNECOL, 1989, 161: 69-72;
    [6] Kristin R , etal. Bleomycin-Ifesfamide cis-platinem (BIP) in Pelvic Recurrence of Previously Irradiated cervical carcinoma: A seconl look. Gynecol Oncol, 1992, 46: 203-207;
    [7] Hockle M, etal. The Combined Operative and Raditherapeutic Treatment (LORT) of Recur rent Tumors Infiltrating the PelvicWall: First Experience with 18 Patients. Gynecol Oncol , 1992, 46: 20-28;
    [8] Koji H, etal. Combination Chemotherapy with 254-S, Ifosfamide and Peplomycin for Advanced or Recurrent Cervical Cancer. Cancer, 1993, 71: 2769-2775;
    [9] Casper Es.Kepsen Dp.Alcoor NW, etal. Ip Cisplatin in patients with malignant ascites: pharmacokinetic evaluation and comparison with the IV route. Cancer Treat Rep, 1983, 67: 235;
    [10] Lopez JA. Clinical pharmaclogy of intraperitoneal cisplatin.Gynecol Oncol, 1985, 20: 1;
    [11] 韩国容, 察桂凤.顺铂腹腔化疗的药代动力学研究.中华妇产科杂志, 1993, 28: 4;
    [12] 李大鹏.康莱特注射液研究总法.浙江省中医院药物研究室, 1996.
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出版历程
  • 刊出日期:  1999-08-04

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    • Hubei Provincial Cancer Hospital, Wuhan 430079

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