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循环肿瘤细胞的富集与检测研究进展

胡玉倩, 谢圣高, 郑 义, 宁 勇

胡玉倩, 谢圣高, 郑 义, 宁 勇. 循环肿瘤细胞的富集与检测研究进展[J]. 肿瘤防治研究, 2014, 41(07): 834-838. DOI: 10.3971/j.issn.1000-8578.2014.07.032
引用本文: 胡玉倩, 谢圣高, 郑 义, 宁 勇. 循环肿瘤细胞的富集与检测研究进展[J]. 肿瘤防治研究, 2014, 41(07): 834-838. DOI: 10.3971/j.issn.1000-8578.2014.07.032
HU Yuqian, XIE Shenggao, ZHENG Yi, NING Yong. Review on Enrichment and Detection of Circulating Tumor Cells[J]. Cancer Research on Prevention and Treatment, 2014, 41(07): 834-838. DOI: 10.3971/j.issn.1000-8578.2014.07.032
Citation: HU Yuqian, XIE Shenggao, ZHENG Yi, NING Yong. Review on Enrichment and Detection of Circulating Tumor Cells[J]. Cancer Research on Prevention and Treatment, 2014, 41(07): 834-838. DOI: 10.3971/j.issn.1000-8578.2014.07.032

循环肿瘤细胞的富集与检测研究进展

基金项目: 教育部新教师基金资助项目(20090002120055)
详细信息
    作者简介:

    胡玉倩(1990-),女,硕士在读,主要从事肿瘤的分子生物学研究

    通信作者:

    谢圣高,E-mail:xiesg100@163.com

  • 中图分类号: R73-37;R730.43

Review on Enrichment and Detection of Circulating Tumor Cells

  • 摘要: 肿瘤的复发和转移是导致死亡的主要原因。循环肿瘤细胞(CTCs)与肿瘤的转移密切相关。CTCs因其表面分子的多样性可为临床诊断、预后和个性化治疗提供丰富的信息。CTCs富集方法极为重要,其表面分子的检测以及临床应用都受到富集方法的制约。目前,CTCs富集检测方法日新月异,本文针对CTCs富集检测方法作一综述。

     

    Abstract: Tumor relapse and metastasis are the main reasons for cancer related deaths. Circulating tumor cells(CTCs) are believed to be correlated to tumor metastasis closely. As the multiplicity of CTCs surface molecule, CTCs have potential to provide sufficient information in clinical diagnosis, prognosis and individualized cancer treatment. The methods of CTCs enrichment are considered to be extremely important because the clinical application and molecular characterization of CTCs are restricted to it. Nowadays, the technologies that are proposed to isolate CTCs are developing rapidly. This paper mainly summarizes the progression of the enrichment and detecting methods of CTCs.

     

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出版历程
  • 刊出日期:  2014-07-24

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