我国淋巴瘤的临床病理特点──附1289例分析
Malignant lymphomas in China an Analysis of 1289 Cases
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摘要: 将解放军总医院自1955至1993年38年中250000例活检材料中原诊断为淋巴瘤的1289例切片进行重新阅片,根据1994年国际淋巴瘤研究组的分类方案进行分型,从性别?年龄?部位?发病率的动态变化?类型共5方面与欧美淋巴瘤进行比较,结果发现,我国淋巴瘤与欧美有着诸多的不同,其特点是:(1)男女比例高;(2)仅有一个年龄高峰;(3)结外淋巴瘤多于淋巴结;(4)缺乏逐年发病率增高趋势;(5)何杰金氏病少见?这5点初步结果显示出我国淋巴瘤与欧美存在着显著的差异,值得进行更进一步的研究?Abstract: All histological slides were reviewed and a comparative analysis was performed on 1289 cases of malignant lymphomas reported from 250000 cases biopsies during the 38 years period from 1955 through 1993 in the files of the Department of Pathology,Chinese PLA General Hospital, Beijing.Five distinctions were found in these Chinese cases of lymphomas: (1) high rate of male:female(2. 8:1);(2) only one peak of the incidence(20-30 years old);(3) high rate of the extranodal lymphomas (53.7);(4) no increasing incidence by year;(5) low rate of Hodgkin's disease(4.6%).The distinctive difference of malignant lymphomas between China and Western suggest the possibility for the next research.
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Key words:
- malignant lymphoma /
- classification /
- comparative pathology
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1 Dorfman RF. Classification of non-Hodgkins lymphomas. Lancet, 1974, ii;1295. 2 Chan ]KC, Banks PM, Cleary ML, et al. A proposal for classification of lymphoid neoplasms (by the International Lymphoma Study Group ). Histopathology,1994, 25:517. 3 Cutler S], Young ]L. Third National Cancer Survey;Incidence data. Natl Cancer Inst Monogr, 1975, 41:1. 4 Anonymous. Cancer statistics, 1979; 29:6. 5 Knowle9 DM. The extranodal lymphoid infiltrate: Adiagnostic dilemma. Seminars Diag Pathol, 1985, 2:147. 6 Stukonis MK. Cancer incidence cumulative rates. IARC internal Technical Report NO. 78/002. Lyon, IARC, 1978. 7 顾绥岳.9009例恶性淋巴瘤病理学分类的回顾性研究.淋巴瘤学刊，1983, 7:1.
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