DIAGNOSIS OF ANGI0IMMUNOBLASTIC LYMPHADENOPATHY

The clinical and pathologic findings ih 14 patients with angioimmunoblastic lymphadenopathy(AILD)are presented.The patients' ages ranged from 5 to 67 yearswith a median age of 43 years. This series included 8 men and 6 women. Theclinical presentation is suggested as malignant lympboma. All of the patients hadlymphadenopathy, 10 patients had fever, 7 had hepatomegaly, 7 splenomegaly, 5severe anemia and skin rashes in two. Hypergammaglobulinemia was found in 5of 6 patients. Four patients was die of disease rapidly (6 to 12 month) afterdiagnosis. Moreover, immunoblastic sarcoma was appeared in autopsy. The main fea-tures of pathology are: extensive alteration in the nodal architecture, abundantsmall vessels with hyperplasia endothelium, pronounced proliferation of immuno-blasts and pre-plasmacytes and plasmacytes with varied infiltration of acidocytes.