Advanced Search
Wang Shun-xiang, . ASSAY OF URINARY POLYAMINES IN PATIENTS WITH CANCER OF ALIMENTARY CANAL[J]. Cancer Research on Prevention and Treatment, 1994, 21(1): 11-14.
Citation: Wang Shun-xiang, . ASSAY OF URINARY POLYAMINES IN PATIENTS WITH CANCER OF ALIMENTARY CANAL[J]. Cancer Research on Prevention and Treatment, 1994, 21(1): 11-14.

ASSAY OF URINARY POLYAMINES IN PATIENTS WITH CANCER OF ALIMENTARY CANAL

More Information
  • The amounts of urinary polyamines of 161 patients with cancer of allmentary canai were determined.The urinary polyamines in these patients were significantly higher than those in normal subjects.The putrescine,spermidine and spermine had respectively increased by 0.86 to 2.28 times,0.11 to 0.72 times and 2.76 to 5.17 times.Of the patients,88.0% to 100% had arise in one of the three polyamines while 60.87% to 80.0% in two.Between the putrescine and spermidine in the electrophoregram a histamine-like substance was detected.Whose value was also high,and 1.02 to 1.48 times higher than the normal value with a positive elevated rate of 47.06% to 60.42%.Patients' urinary polyamines were reduced as shown by repeated assay maed in 21 cases postoperatively and 2 cases after chmotherapy.The assay of urinary polyamine can be used as an auxiliary method in the clinical diagnosis and therapeutical evaluation of cancer of alimentary canal.
  • 1. Russell DH,et al.Urinary folyamines in cancer patients.Cacner Res,1971,31:1555
    2. Fupjita K,et al.Urinary putressine,Spermidine,and Spermine in human blood and Solid cancers and in a experimental gastric tumor of rats.Cancer Res,1976,36:1320
    3. Russell DH,et al.clenical relevance of polyamines as biochenical markers of tumor kinetics. clin chem, 1977,23:22
    4. Russell DH,et al.polyamines as predictars of Success and failure in cancer chemotherapy. Lancet,,1975,2:797
    5. Nichioka R,et al.Serum polyamines alteration in Surgical patients with colarectal carcinoma. J Surg oncol,1977,9:555
    6. 范慕贞,等.食管癌病人尿中多胺的测定.中华医学杂志,1979,2:98
    7. 黄品忠,等.尿中多胺测定对消化系统恶性肿瘤的诊断价值.新医学,1982,8:404
    8. 王顺祥,等.尿多胺的柱层析——常压滤纸电泳比色测定法.临床检验杂志,1988,1:2
    9. 上海市医学化验所.临床生化检验.上海科学技术出版社,1982,109
    10 许绍辉,等.正常人尿中多胺值与性别的关系及其在肿瘤诊断中的意义.解放军医学杂志,1983,2:139
    11 王顺样,等.食管癌患者癌组织的多胺含量分析.癌症,1987,4:258
    12 上海第一医学院.医用生物化学.上册.人民卫生出版杜,1979.786
    13 赵君庸.多胺的生理功能和临床意义.国外医学临床生物化学与检验学分册,1983,1:22
    14 Ionue H,et al.A New method for isolation of polyamine from animal tissues.Anal Biochern,1973,56:408

Catalog

    Article views (1450) PDF downloads (368) Cited by()

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return