The Clinicopathology and Immunohistochemical Study of Esophagus Small Cell Carcinoma

Objective study the clinic pathological character and histogenesis of primary esophagus small cell cancer. Methods use the immunohistochemistry. Results 7 cases were pure small cell types,4 intermediate types,3 combined types.Immunohistochemically,ten cases showed positive immunoreaction to cytokeratin.EMA.NSE.Chromogranin A Synaptophysin 12.13.6.4 cases,respectively.Among the patients which obtained follow have 6 case died within half year. Conclusion this study indicate that small cell carcinoma of esophagus is highly malignancy,support its histogenesis may origin from the multipotent stem cells.