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Zhao Aiguang, Yang Jinkun, Xiao Zhuoxiang, . The Effect of SRRS Prenventing P 53 Gene from Mutation[J]. Cancer Research on Prevention and Treatment, 1999, 26(3): 181-183.
Citation: Zhao Aiguang, Yang Jinkun, Xiao Zhuoxiang, . The Effect of SRRS Prenventing P 53 Gene from Mutation[J]. Cancer Research on Prevention and Treatment, 1999, 26(3): 181-183.

The Effect of SRRS Prenventing P 53 Gene from Mutation

  • In order to study the mechanism of the tumor suppressor effect of the “SRRS”,a recipe composed of some Chinese herbs,the mutation of P 53 gene exon 7 in the tumor tissue was observed by PCR SSCP in the nude mice Lovo transplantation tumors.The important observation of this study was that none of the samples(0/10)was shown to have P 53 gene exon7 mutation in the experimental group which SRRS was taken.After all,50%(5/10) of the samples were shown to have P 53 mutation in the control group.This result suggested that SRRS could prevent P 53 gene from mutating during the Lovo transplatstion tumors growing.
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