The Changes of Number and Activity of Natural Killer Cells during Mobilization by Cyclophospamide and G-CSF

Objective To study the changes of number and activity of natural killer(NK) cells during the cancer patients mobilization by cyclophosphamide(CY) and recombinant human granulocyte colony stimulating factor(G CSF). Methods Peripheral blood CD 34 + cells and NK cells(CD - 3CD + 16 CD 56 +) were counted using flow cytometry on the day before mobilization (baseline),the day of WBC nadir(nadir),3 days after the nadir(early recovery phase),six days after the nadir(recovery phase) in 21 cancer ...