Relationship among telomerase activity and bcl-2 and bax in breast cancer
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Abstract
Objective To investigate the role of detection of telomerase activity in breast cancer diagnosis and the correlation of telomerase and bcl-2 and bax in the genesis of breast cancer. Methods With in situ hybridzation to detect the expression and activity of telomerase. bcl-2 and bax were studied by strept Avidin-Biontin Complex immunohistochemistry(SABC). Results The expression rate of telomerase in breast cancer was significantly higher than that in precancerous breast( P <0.01) and in breast beni...
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