Expression of cyclin D_2 in Hodgkin s Lymphoma and Anaplastic Large Cell Lymphoma and Its Significance

Objective To detect the expression of cyclin D 2 in HL and ALCL at the level of protein and to investigate the roles of this gene in the pathogenesis of HL and ALCL. Methods Selecting the cases of HL and ALCL from 288 cases of malignant lymphomas. The clarified 26 paraffin embed tissue, comprising cases of 26 cases of HL and 19 cases of ALCL were finally subjected to immunohistochemical staining to analyze the expression of cyclin D 2. Results The positive rate of cyclin D 2 expression in HL and in ALCL...