Advanced Search
YA Han-qing, WANG Wei-xing, HUANG Shun-rong, XU Sheng. Effects of Total Parenteral Nutrition Supplemented with Glutamine and Arginine on Postoperative Immune Function in Patients with Colorectal Cancer[J]. Cancer Research on Prevention and Treatment, 2007, 34(12): 965-967. DOI: 10.3971/j.issn.1000-8578.50
Citation: YA Han-qing, WANG Wei-xing, HUANG Shun-rong, XU Sheng. Effects of Total Parenteral Nutrition Supplemented with Glutamine and Arginine on Postoperative Immune Function in Patients with Colorectal Cancer[J]. Cancer Research on Prevention and Treatment, 2007, 34(12): 965-967. DOI: 10.3971/j.issn.1000-8578.50
shu

Effects of Total Parenteral Nutrition Supplemented with Glutamine and Arginine on Postoperative Immune Function in Patients with Colorectal Cancer

  • 1. Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China ( Present :Department of Gastroenterology Surgery, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021) ;2. Department of Hepatobi liary & Laparoscopic Surgery, Renmin Hospital of Wuhan University ; 3. Department of Gastroenterology Surgery, The People' s Hospital of Guangxi Zhuang Autonomous Region

More Information
  • Corresponding author:

    YA Han-qing

  • Received Date: January 15, 2006
  • Revised Date: July 26, 2007
    Graphical Abstract
    • Abstract
  • Objective 　To study the effect of total parenteral nut rition ( TPN) supplemented with glutamine and arginine on the postoperative immune function of the patient s with colorectal cancer. Methods 　According to the operative methods with match, the patient s with colorectal cancer between August 2005 and August 2006 were divided into experiment group and control group, including 24 cases respectively. From the first day to the seventh day af ter operation, TPN supplemented with glutamine and arginine was used in the experiment group, while standard TPN was used in the control group. The humoral immune markers ( IgA, IgG, IgM) and cellular immune markers (CD3, CD4, CD8, CD4/ CD8) were measured in all cases before the operation, on the fourth day and the eighth day af ter operation. Results 　Compared with the preoperative immunity, the levels of humoral and cellular immunity declined on the fourth day, but they resumed on the eighth day after operation. Compared with the cont rol group, IgA、IgG、CD3 、CD4 、CD4/CD8 in the experiment group on the eighth day af ter operation increased significantly ( P < 0. 05) . Conclusion 　TPN supplemented with glutamine and arginine can improve the immune function of patient s with colorectal cancer after operation effectively.
    • FullText(HTML)
    • References (0)
    • Related Articles

  • Related Articles

    [1]CHU Xuelei, AN Chen, XI Lingze, XIE Hongting, ZONG Mingtong, XUE Peng, ZHU Shijie. Predictive Value of Immune Inflammation Combined with Liver Function Hematological Indicators for Metastasis of Colorectal Cancer[J]. Cancer Research on Prevention and Treatment, 2024, 51(9): 764-771. DOI: 10.3971/j.issn.1000-8578.2024.24.0211
    [2]LIANG Xin, LIANG Xinjun, WEI Shaozhong. Predictive Value of Pan-immune-inflammation Value for Prognosis of Patients with Resectable Colorectal Cancer[J]. Cancer Research on Prevention and Treatment, 2023, 50(5): 505-511. DOI: 10.3971/j.issn.1000-8578.2023.23.0150
    [3]LIU Jianbo, LI Baiyu, KE Shanbao, ZHANG Wei. Cordycepin Attenuates Immune Function Injury in A Rat Model of Lung Cancer After Radiotherapy by Inhibiting JAK2/STAT3 Pathway[J]. Cancer Research on Prevention and Treatment, 2021, 48(11): 994-998. DOI: 10.3971/j.issn.1000-8578.2021.21.0094
    [4]CAO Qihua, XU Yanbo, XU Dong. Research Progress of Immune Checkpoint Therapy on Colorectal Cancer[J]. Cancer Research on Prevention and Treatment, 2021, 48(3): 229-233. DOI: 10.3971/j.issn.1000-8578.2021.20.1060
    [5]ZHOU Xingqin, ZHAO Hongyu, SONG Yao, CHEN Wenjuan, SHEN Chaoyan, JI Bin. Therapeutic Effect of Elemene Combined with Chemoradiotherapy and Its Influence on Immune Function in Nasopharyngeal Carcinoma Patients[J]. Cancer Research on Prevention and Treatment, 2019, 46(12): 1118-1122. DOI: 10.3971/j.issn.1000-8578.2019.19.0669
    [6]CHEN Jinghua, TAN Wenyong, XU Ruilian, XIA Junxian, ZHU Meiqin. Clinical Efficacy of Gemcitabine plus S-1 on Refractory Nasopharyngeal Carcinoma Patients and Their Influence on Immune Function[J]. Cancer Research on Prevention and Treatment, 2018, 45(12): 1014-1019. DOI: 10.3971/j.issn.1000-8578.2018.18.0443
    [7]YANG Xinrui, WANG Gang, JI Libin, WANG Haiyan. Effects of Arenaria Kansuensis Aqueous Extract on Immune Function of H22 Tumorbearing Mice[J]. Cancer Research on Prevention and Treatment, 2015, 42(07): 662-665. DOI: 10.3971/j.issn.1000-8578.2015.07.005
    [8]CAI Bin, XU Yangxian, JIANG Haitao, YANG Jiyong, SUN Xun, LIN Tianbi, ZHANG Xuelin, ZHANG Jingzhe. Effect of Yiqi Yangyin Recipe Combined with FOLFOX4 on Immune Function in Patients with Colorectal Cancer[J]. Cancer Research on Prevention and Treatment, 2014, 41(08): 932-935. DOI: 10.3971/j.issn.1000-8578.2014.08.017
    [9]Zheng Guangyao, He Ling, Zhou Taotao, Li Ruoda, Bo Caiying, Xie Xuerong. Anti-tumor Effects of Chlorophyll-carotene Paste from Pine Needles and Immune Function in Sarcoma S180 Tumor-bearing Mice[J]. Cancer Research on Prevention and Treatment, 2012, 39(11): 1324-1327. DOI: 10.3971/j.issn.1000-8578.2012.11.011
    [10]Huang Guo, . Effect of low ionizing radiation on tumor metastasis and immune function of mice[J]. Cancer Research on Prevention and Treatment, 1996, 23(3): 160-163.

Catalog

    Get Citation
    PDF
    XML
    Article views (2489) PDF downloads (788) Cited by()
    Turn off MathJax
    Article Contents
    Abstract
    Related Articles

    Download Center

    Links

    Contact Us

    Address：116 Zhuodaoquan South Road,
    Hongshan District, Wuhan（430079）

    Tel：027－87670126

    Email：zlfzyjzz@vip.163.com

    This work is licensed under a Creative Commons Attribution 3.0 License.

    Email Alert RSS
    Total visits：18940540 Visits today：20882

    Copyright © Editorial Department of Cancer Prevention Research 鄂公网安备 42011102005013号 鄂ICP备2022015867号

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return