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YANG Hong-wu, QU Chong-xiao, GUAN Hong-wei. Arsenic Trioxide Reversing the Multidrug Resistance of Gastric Carcinoma Cell Line SGC7901/ADR to Adriamycin[J]. Cancer Research on Prevention and Treatment, 2006, 33(03): 148-150. DOI: 10.3971/j.issn.1000-8578.445
Citation: YANG Hong-wu, QU Chong-xiao, GUAN Hong-wei. Arsenic Trioxide Reversing the Multidrug Resistance of Gastric Carcinoma Cell Line SGC7901/ADR to Adriamycin[J]. Cancer Research on Prevention and Treatment, 2006, 33(03): 148-150. DOI: 10.3971/j.issn.1000-8578.445
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Arsenic Trioxide Reversing the Multidrug Resistance of Gastric Carcinoma Cell Line SGC7901/ADR to Adriamycin

    Abstract
  • Objective To explore the reversal effect of Arsenic trioxide(As_ 2O_ 3) on multidrug resistance of gastric tumor cell line SGC7901/ADR to adriamycin(ADM)and the impact of As_ 2O_ 3 to the expressions of P-gp and GST-π in SGC7901/ADR cells. Methods Multidrug resistant human gastric carcinomas cell line SGC7901/ADR was used as target cells,the sensitivity of cell to adriamycin was assessed with MTT assay,the drug concentration in cells was detected with flow cytometry(FCM),and the impact of arsenic trioxide t...
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