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CHEN Hui-jun, WU Xu-feng, CHEN Hui-zhen. The Role of TopoⅡα、GST-π、P-gp Played in the Multidrug Resistance of the Epithelial Ovarian[J]. Cancer Research on Prevention and Treatment, 2006, 33(03): 197-199，. DOI: 10.3971/j.issn.1000-8578.429
Citation: CHEN Hui-jun, WU Xu-feng, CHEN Hui-zhen. The Role of TopoⅡα、GST-π、P-gp Played in the Multidrug Resistance of the Epithelial Ovarian[J]. Cancer Research on Prevention and Treatment, 2006, 33(03): 197-199，. DOI: 10.3971/j.issn.1000-8578.429
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The Role of TopoⅡα、GST-π、P-gp Played in the Multidrug Resistance of the Epithelial Ovarian

  • Department of Gynecology Oncology; Zhongnan Hospital of Wuhan University; Wuhan 430071; China

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  • Corresponding author:

    WU Xu-feng

  • Received Date: August 08, 2005
  • Revised Date: December 26, 2005
    Abstract
  • Objective To investigate the role TopoⅡα、GST-π、P-gp played in multidrug resistance of the epithelial ovarian carcinoma. Methods The expression of TopoⅡα、GST-π、P-gp in 80 cases of ovarian carcinoma, 20 cases of benign ovarian tumor and 20 cases of normal control were determined by SP immunohistochemical technique. Results The positive expression rate of TopoⅡα、GST-π、P-gp in ovarian carcinoma was significantly higher than in benign tumors and normal tissues, P< 0.05. A significant relationship was shown be...
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    CHEN Hui-zhen

    • Department of Gynecology Oncology; Zhongnan Hospital of Wuhan University; Wuhan 430071; China

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