Effects of 9-cis-Retinoic Acid on the Expression of CD44 and CD54 in Lung Cancer Cell Lines

Objective To study the effect of 9-cis-retinoic acid (9-cis-RA) on the expression of both CD44 and CD54 in lung cancer cells. Methods 9-cis-RA (1umol/L) was used to treat lung cancer cells; Flow cytometry (FCM) was used to detect the positive marked rate of both CD44 and CD54 of three groups including blank control, DMSO control and 9-cis-RA groups. Results In PG cells, the marked rate of CD44 was significantly lower and the marked rate of CD54 was higher than that of the control groups; In A549 cells, simi...