Expression of Nuclear Factor κB and Its Relationship with VEGF、p53 Proteins in Pancreatic Cancer

ZHANG Ke-jun; LI De-chun

doi:10.3971/j.issn.1000-8578.375

ZHANG Ke-jun, LI De-chun. Expression of Nuclear Factor κB and Its Relationship with VEGF、p53 Proteins in Pancreatic Cancer[J]. Cancer Research on Prevention and Treatment, 2006, 33(11): 805-807. DOI: 10.3971/j.issn.1000-8578.375

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Expression of Nuclear Factor κB and Its Relationship with VEGF、p53 Proteins in Pancreatic Cancer

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Objective To study the expression of nuclear factor kappab gene(NF-κB) and its relationship with expression of VEGF、p53 proteins in pancreatic cancer(PC). Methods The expression of NF-κB、IκB-a was investigated by Western blot in PC samples,parocarcinoma tissues,chronic pancreatitis(CP)samples and normal pancreatic(NP) samples. The activity of NF-κB was detected through eletrophoretic mobility shift assay(EMSA) in PC,CP and NP samples.Immunohistochemical analysis for VEGF,p65,p53. Results The positive expres...

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Expression of Nuclear Factor κB and Its Relationship with VEGF、p53 Proteins in Pancreatic Cancer

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