The Relationship of GSTT1 Polymorphism and Chromosome 15 Aberration in Lung Cancer Patients

Objective The research analyzed the difference of GSTT1 genotype polymorphism between lung cancer cases and controls,evaluated the association of the genetic polymorphism and aberration of chromosome 15 with lung cancer. Methods GSTT1 genotypes from 61 lung cancer cases and 46 controls were determined by PCR and structural and number aberration of chromosome 15 were detected by FISH. Results There was no any differences of distribution of GSTT1 positive(+/+ and +/0) and GSTT1 null(0/0) genotypes between case