Expression of Fas、FasL、bcl-2 protein in colorectal carcinomas
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Abstract
Objective To investigate the significance of Fas?FasL and bcl 2 in human colorectal carcinoma. Methods The expression of Fas?FasL and bcl 2 protein were detected by immunohistochemical method in paraffin sections of 15 cases of colorectal adenomas? 40 cases of colorectal carcinomas and 15 cases of normal colorectal mucous. The TdT mediated dUTP biotin nick and labeling(TUNEL) positive were counted in all cases as apoptosis index(AI). Results AI in colorectal carcinoma was higher than in normal t...
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