The expression significance of extracellular signal-regulated kinase in bladder cancer

Objective To investigate the role of extracellular signal regulated kinase (ERK) 1 in pathogenesis of bladder cancer and its relationships with tumor biological behaviors and fibroblast growth factor receptor (FGFR) and c met. Methods ERK1,FGFR and c met expressions were determined by immunohistochemistry technique in 88 cases with bladder cancer and 9 cases with normal bladder tissues. DNA parameters in patients with bladder cancer were determined by DNA image cytometry. Results The positive expres...