The Prognostic Significance of P-glycoprotein,Mutant p53 Protein and Epidermal Growth Factor Receptor Expression in Primary Transitional Cell Carcinoma of Bliadder

Objective The study investigates the prognostic significance of P-glycoprotein(Pgp),mutant p53 Protein and epidermal growth factor receptor (EGFR)expression in primary transitional cell carcinomas of bladder . Methods 83 human primary bladder TCC of previous untreat patients with over 3 years follow-up were analysed for expressin of Pgp,Mutant p53 and EGFR by means of SP immunohischemistry(IHC).The mouse s monoclonal antibodies of JSB1.DO-7 and 32G7 were carried out to deteced the antigens of Pgp,p53 and EG...