Expression Pattern and Clinical Significance of E-cadherin in Squamous Cell Carcinoma of Cervix

Objective To study the expression pattern and clinical significance of E-cadherin (ECD) in cervical squamous cell carcinoma. Methods We used SP immunohistochemical method to study ECD expression in 42 cervical squamous cell carcinomas.The survival was analyzed by Kaplan-Meier survival curve,Log-rank test and Cox regression model. Results (1) ECD membranous and cytoplasmic expressions were found simultaneously in cervical squamous cell carcinoma.High membranous expression was more frequent in Ⅰ,Ⅱ grade tumo...