Monomorphic Analysis of Microsa tellite Lociat BAT-26

Objective MSI plays an important role in carainogenesis of mant tumors.Most MS loci show polymorphism in normal tissues.It has been reported that BAT-26 was quasi-monomorphic,showing only minor size variathions.To analysis monomorphism at BAT-26 loci,60 normal colorectal tissues were examined. Methods Genomic DNA extracted from tissues was PCR amplified.PCR products were run on 6% denaturing polyacrylamide gel and stained with silver. Results All specimens showed no variation in the length of MS DNA at BAT...