Effect of Kudzu Flavonoids Extracts on Proliferation and Apoptosis of HL-60 Cells

Objective To investigate the effect of Kudzu flavonoids extracts on human leukaemia cancer cells HL-60 line to reveal its probable mechanism. Methods The survival and proliferation of HL-60 cells were determined by MTT.The cell-DNA ploidy distribution and apoptotic rate were measured by flow cytometry (FCM), and DNA ladder.The differentiation induced potence was determined by NBT. The anticancer and apoptosis potence induced by flavonoids detected by TUNEL. Results There was significant inhibition of the ce...