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LIU Jun-li, CHEN Yuan, CAI Yu. Effect of Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor ZD1839 on Cervical Carcinoma Cells[J]. Cancer Research on Prevention and Treatment, 2006, 33(07): 512-515. DOI: 10.3971/j.issn.1000-8578.2286
Citation: LIU Jun-li, CHEN Yuan, CAI Yu. Effect of Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor ZD1839 on Cervical Carcinoma Cells[J]. Cancer Research on Prevention and Treatment, 2006, 33(07): 512-515. DOI: 10.3971/j.issn.1000-8578.2286
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Effect of Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor ZD1839 on Cervical Carcinoma Cells

    Abstract
  • Objective To investigate the effect of a selective epidermal growth factor receptor(EGFR) ZD1839 on cervical carcinoma cells. Methods The effect of ZD1839 on cervical carcinoma cells(Siha,Hela) was determined by MTT assay.The effect of ZD1839 combined with cisplatin(DDP) on cervical carcinoma cells was also evaluated.Burgi formula was adopted to analyze combination effect.The distribution of cell cycle and cell apoptosis rate were analyzed by flow cytometry. Results The proliferation of cervical carcinoma cel...
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