Expression of cyclooxygenase 2 protein and its relationship with bcl-2 in non-small cell lung cancer

Objective To investigate the expression of cyclooxygenase 2 (COX-2) protein and its relationship with bcl-2 in non-small cell lung cancer(NSCLC). Methods Immunohistochemical assay was used to detect the localization of COX-2 protein expression in cancerous tissues and paired noncancerous tissues from 53 patients, and the semi-quantitative COX-2 protein was evaluated by Western blot. bcl-2 protein was detected by immunohistochemical assay. Results Expression of COX-2 protein was significantly higher in ca...