Immunophenotype and Epstein-Barr Virus Infection and Detection Rearrangement of T Cell Receptor γ(TCRγ) Gene in Nasal NK/T-cell Lymphoma
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Abstract
Objective To explore the immunophenotype and Epstein-Barr Virus(EBV) infection of nasal NK/T cell lymphoma and the significance of detection rearrangement of TCR γ gene in diagnosis and differential diagnosis of nasal NK/T cell lymphoma. Methods Fouty-eight cases of nasal NK/T cell lymphoma were studied, immunophenotype was analyzed by immunohistochemical staining for LCA、CD79α、CD20、CD56、CD3、CD45RO and EBV with SP method. In situ hybridization (ISH) with EBER1/2RNA probes was perfomed.TCR γ gene rearrangeme...
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