Therapeutic Progress in Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer

LIU Yi; HUANG Zhen; CHEN Lulu; SONG Qibin

doi:10.3971/j.issn.1000-8578.2025.25.0438

LIU Yi, HUANG Zhen, CHEN Lulu, SONG Qibin. Therapeutic Progress in Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer[J]. Cancer Research on Prevention and Treatment. DOI: 10.3971/j.issn.1000-8578.2025.25.0438

Citation:

LIU Yi, HUANG Zhen, CHEN Lulu, SONG Qibin. Therapeutic Progress in Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer[J]. Cancer Research on Prevention and Treatment. DOI: 10.3971/j.issn.1000-8578.2025.25.0438

Citation:

LIU Yi, HUANG Zhen, CHEN Lulu, SONG Qibin. Therapeutic Progress in Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer[J]. Cancer Research on Prevention and Treatment. DOI: 10.3971/j.issn.1000-8578.2025.25.0438

Therapeutic Progress in Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer

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Abstract

This article elucidates therapeutic approaches for KRAS G12C-mutant advanced non-small cell lung cancer, with focus on global advancements in inhibitor research. It also summarizes clinical evidence on the efficacy of targeted agents in monotherapy and combination therapies, analyzes their clinical advantages and challenges, and explores future directions for novel treatment modalities.

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Therapeutic Progress in Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer

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