Epigenetic Mechanism of DNA Virus-mediated Carcinogenesis
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Abstract
Various kinds of virus could lead to carcinogenesis. Although those viruses belong to different viraceae, the molecular mechanisms they have evolved to cause tumor initiation show many similarities, which are targeting the key cellular proteins that regulate cell growth and proliferation. The interactions between virus and hosts occur at epigenetic level. This review summarizes the epigenetic mechanism of DNA virus proteins contributing to carcinogenesis.
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