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FU Chun, LI Guang-yi, LIU Xiao-ying, LIN Qiu-hua, LIU Feng-ying, XIE Yong. Cisplatin-Induced Apoptosis in Cisplatin-resistant Ovarian Cancer Cell Line A2780/DDP on Time- and Dose- Dependence[J]. Cancer Research on Prevention and Treatment, 2006, 33(08): 561-564. DOI: 10.3971/j.issn.1000-8578.1831
Citation: FU Chun, LI Guang-yi, LIU Xiao-ying, LIN Qiu-hua, LIU Feng-ying, XIE Yong. Cisplatin-Induced Apoptosis in Cisplatin-resistant Ovarian Cancer Cell Line A2780/DDP on Time- and Dose- Dependence[J]. Cancer Research on Prevention and Treatment, 2006, 33(08): 561-564. DOI: 10.3971/j.issn.1000-8578.1831
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Cisplatin-Induced Apoptosis in Cisplatin-resistant Ovarian Cancer Cell Line A2780/DDP on Time- and Dose- Dependence

  • 1.Department of Obstetrics and Gynecology; The First People's Hospital of Foshan; Foshan 528000; China; 2.The Sixth Hospital of Guangzhou; 3.The Second Xiangya Hospital; Central South University

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    FU Chun

  • Received Date: August 14, 2005
  • Revised Date: October 25, 2005
    Abstract
  • Objective To investigate the law during cisplatin-induced apoptosis in cisplatin-resistant and sensitive human ovarian cancer cell line A2780 and A2780/DDP and correlative protein expressions in mitochondria apoptotic pathway. Methods Two ovarian cancer cell lines,one is cisplatin-sensitive line A2780 and the other is resistant-line A2780/DDP,were selected.Based on cell culture,the influence of varied doses(5,10,20,40μM) and time(24,48,72h) of cisplatin on apoptosis in A2780 and A2780/DDP cell lines and prot...
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    XIE Yong

    • 1.Department of Obstetrics and Gynecology; The First People's Hospital of Foshan; Foshan 528000; China; 2.The Sixth Hospital of Guangzhou; 3.The Second Xiangya Hospital; Central South University

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