Polymorphisms of 5,10-Methylenetetrahydrofolate Reductase and Risk of Lung Cancer in Guangdong Population

Objective To study the relation between polymorphisms of N 5,10 -methylenetetrahydrofolate reductase(MTHFR) and susceptibility of lung cancer. Methods We conducted a case control study with 100 cases of lung cancer and 100 population based controls in Guangdong province. MTHFR genotypes were detected by PCR-RFLP method. Results The expressions of MTHFR genotypes have a statistically significant difference between lung cancer and healthy people(P= 0.030). And there are on such difference among different gender...