Plasma endothelin in breast cancer before and after chemotherapy

Objective To evalue the value of plasma endothelin-1(ET-1) in predicting the prognosis of breast cancer patients before and after chemotherapy. Methods Radioimmunoassay was available to detect the level of plasma ET-1 in 20 cases of normal control subject and 45 cases of patients with breast cancer before and after chemotherapy. Results Level of plasma ET-1 were elevated in all subgroups of patients with breast cancer compared to the controls ( P <0.01), the plasma ET-1 level in stage Ⅳ was hi...