Expression and Significance of MMP-9、EGFR and E-cadherin in NSCLC

Objective To study the clinical significance of the expression of matrix metalloproteinase-9(MMP-9)、epidermal growth factor receptor (EGFR)、E-cadherin(E-cad) in patients with non-small cell lung cancer(NSCLC). Methods Immunohistochemical method (SP) was used to detect the expression of the MMP-9、EGFR、E-cad in 62 NSCLC tissues and 18 normal lung tissues. Results (1) The positive expression rates of MMP-9 and EGFR were 67.7%、 58.1% respectively in the 62 NSCLC. The abnormal expression rate of E-cad w...