Expression of Cyclooxygenase-2 in Human Breast Invasive Carcinoma and Its Significance
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Abstract
Objective To study the expression of cyclooxygenase -2(COX-2) in breast invasive carcinoma and its clinicopathologic significance. Methods The expression of COX-2 was detected with SP immunohistochemical analysis in 83 cases of breast invasive carcinoma (including 62 cases with surrounding invasion,47 cases with lymph node metastasis) and 35 non-cancerous specimens. Results The positive rate of COX-2 in breast invasive carcinoma was 73.5% (61/83),which was significantly higher than those in non-cancerous...
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