The Treatment of Transplanted Human Nasopharyngeal Carcinoma in Nude Mice with Coixenolide

Objective To study the therapeutic effect of coixenolide (CXL) on the laboratory produced human nasopharyngeal carcinoma. Methods Nude mice bearing human nasopharyngeal carcinoma cell line CNE 2Z were used in observing CXL efficacy . MTT and CUF GM culture assays were adopted to investigate the influence of the drug on immune and hemopoiesis . Results CXL inhibited the tumor growth in a dose response fashion, with a accumulated ID 50 =10 -3.170 mol/kg . The relative potency of CXL is 20.23% ...