Expression of HIF-1α and Its Relationship to Apoptosis and Proliferation in Gastric Cancer Cell During Hypoxia

Objective Investigated the expression of HIF-1α and its relationship to Fas and PCNA, and studied the HIF-1α and its relationship to apoptosis and proliferation in gastric cancer cell during hypoxia. Methods The environment of hypoxia was established by GasPak method. Cell-immunochemistry were used to observe the change of HIF-1α、PCNA and Fas. Results During hypoxia the expression of HIF-1α was upregulated. Inverse relationship was found between the expression of HIF-1α and Fas. There was no relationship be...