Expression of p16 Protein and VEGF in Nasopharyngeal Carcinoma and its Clinical Significance

Objective To investigate the expression of p16 protein and VEGF and its correlation to clinic biological behavior of nasopharyngeal carcinoma (NPC). Methods Expression of p16 protein and VEGF were examined by immunohistochemical staining S-P in 70 cases of NPC and 31 cases of inflammatory nasopharyngeal mucosa. Results The positive expression rate of p16 protein in NPC was significantly lower than it in inflammatory nasopharyngeal mucosa (P< 0.05). The positive expression rate of p16 protein of stageⅠan...