Using Tissue Microarray Technique Research the Expression Meaning of hMSH2 andp16^INK4a in Gastric Cancer

Objective 　This study was to investigate the expression meaning of hMSH2 and p16^INK4a in gastric cancer. Methods 　Gastric cancer tissue microarray(TMA) was formed and tested expression of hMSH2 and 16^INK4a by immunohistochemical methods. Results 　In gastric cancer, the overexpression rates of hMSH2 and 16^INK4ashowed a positive correlation ( r = 0. 23507, P = 0. 0134), which were not related to lymph node metastasis, UICC N stage and prognosis. Conclusion 　the overexpression rates of hMSH2 and 16^INK4a showed a positive correlation and both were not as molecule mark to predict lymph node metastasis, UICCN stage and prognosis.