腹腔灌注免疫调节剂对胃癌患者细胞免疫功能的影响
The Study of Cytoimmune Function About the Therapy of Peritoneal Administration with Immunobiotic Agents to Gastric Cancer
-
摘要: 目的:检测35例进展期胃癌患者手术前后外周血中T细胞亚群的变化,观察免疫生物制剂的作用。方法:应用单克隆抗体和流式细胞仪技术。结果:术后患者CD3和CD4细胞数,CD4/CD8比值比术前下降,术后应用免疫生物制剂的患者CD3和CD4细胞数及CD4/CD8比值高于术前及对照组。结论:腹腔灌注免疫调节剂有利于提高胃癌患者的细胞免疫功能。Abstract: Objective:To measure the change of blood Tlymphocyte subsets of 35 patients who suffered progressive gastric carcinoma before and after operation. Methods:The techniques of monodone antibody and flow cytometry were used. Results:The result indicated that patients CD3 and CD4 cells and the value of CD4/CD8 were lower of ter operation.While in study group of immunobiotic agentswere higher than that of preoperation and control group. Conclusion:It was suggested that peritoneal administration with immunobiotic agents advantage the cytoimmune function of patient with gastric carcinoma.
下载:
