恶性肿瘤血浆激肽释放酶原、纤溶酶原、纤维蛋白原的观察

A STUDY OF PREKALLIKREIN, PLASMINOGEN, FIBRINOGEN IN PATIENTS WITH MALIGNANT TUMOR

摘要: 应用较为先进的检测手段，对84例恶性肿瘤患者血浆激肽释放酶原(PK)、纤溶酶原(PLG)、纤维蛋白原(FIG)进行测定，共100例次。结果表明:PK、PLG明显降低，其中肺癌、消化道癌及白血病降低明显。病情越重，降低越著。本文检测结果提示恶性肿瘤病人纤溶活性增强，存在高凝状态及继发性纤溶，本文还分析了上述指标变化的原因。

Abstract: Plasma levels of prekallikrein (PK), plasminogen (PLG), fibrinogen (FIG) in 84 cases of malignant tumor were studied with an advanced method.Each item was measured 100 times. The results showed that PK, PLG were significant lower than those of control subjects (P0.01), it were low in patients with the cancers of lung, the gastroenteric cancers and leukemias. The more severe the disease condition, the lower was the levels of PK, PLG. It clearly showed that the balance between coagulation and anti-coa-gulation systems was upset in patients with malignant tumor.