DMP方案与DVP方案治疗食管癌54例疗效对比分析

Comparison Between and Analysis of DMP Protocol & DVP Regimen In Curative Effects on 54 Cases or Cancer of the Esophagus

摘要: 我们自1986年1月~1992年6月,用DMP方案(DDP,MMC,PYM)和DVP方案(DDP,VCR,PYM)共治疗食管癌54例.其中DMP方案治疗19例,获RR57.7%,RRR84.2%.DVP方案治疗35例,获RR45.7%,RRR60%.经统计学处理,两方案的完全缓解率,有效率及毒副反应无统计学意义(P>0.05).但从有效率看,DMP方案稍高于DVP方案,DMP方案对初治病人和术后复发转移病人的疗效亦略优于DVP方案.

Abstract: From Jan. 1986 to June 1992, the DMP protocol (DDP, MMC,PYM) and the DVP regimen (DDP, VCR, PYM) were used by us in the management of 54 cases of cancer of the esophagus.of them, 19 cases were treated with the DMP protocol, achieving a 57. 7N RR and a 84.2% RRR; and 35 cases were treated with the DVP regimen, ending in a 45. 7% RR and a 60% RRR. Both of the two regimens were of no statistical significance in terms of complete remission, effective rate and toxic and side effects (P0. 05).There was remarkable difference seen in the total rate of effectiveness from the two methods. The DMP way was superior to the DVP way (P0.05 ). The curative effect of DMP is slightly better than that of DVP, and it is the same in the cases first treated and in those who had relapse and/or metastasis post operation.