Abstract: different ovarian epithelial malignant tumor tissues were assayed for estrogen and progesterone receptors (ER, PR)content with Dextran-coated Charcoal (DCC) method. The resultsshowed that the concentrations of ER and PR in ovarian endometrioid carcinoma were higher thanthat of in ovarian serous,mucous and clear cell carcinomas;The percentage of positive scores forER and PR in ovarian endometrioid and serous malignant tumors were higher than those in otherepithelial malignancies. The contents of ER and PR were associated with the differentiation andmenstrual status. Several ovarian epithelial malignant tumors with high ER and PR concentrations, especilly high PR levels might be a possibility of endocrine therapy. Those patients with ERand PR simultaneous positive hare longer survival period.