Abstract: We have studied enzyme activities in lymphocyte on the lymph node around cancer of 6 casses of the liver cancer by using the electron enzyme histochemical method. Results: 1. The reaction granules of enzyme can be seen clerly beneath the cell membrane aswell as on the surface of endoplasmic reticulum and mitochondria.The tiny granules also can beobserved under the nuclaer membrane and in the chromatin.2. The activities of ATPase and G-6-Pase become lower. 3. The activity of 5'-Nucleotidase is higher.The results suggest that: 1. The decrease of the enzyme activities may be main reasons for thereduce of immunological function in the patients with liver cancer. 2.The chage of enzyme activities can refrect the immunological condition of the patients, differentiation of the tumor and prognosisof the disease.