Abstract: This investigation include 12 patients with centsally located high-stage Lung Cancer. All of them have stage Ⅲ a as stage Ⅲ b lession with pulmonary fixed. All of the 12 cases were operated by pneumonectomy with using the technique of openning and resection part of pericardium to handle main pulmonary vessels and main bronchus. All of the 12 operations had accomplished successfully. ln author's idea, using the technique of intropericardial pneumonectomy may treat some advanced Lung Cancer patients who would not be operated by conventional introthoracic processes,enlarge the extend of operative indication, increase the rate of resectability, improve the parients'survival time and would be being a prospective method in treating centrally located high-stage Lung Cancer.